Human Recombinant G-CSF (from E. coli)
About this item
Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte proliferation, terminal differentiation, and activation. G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, tumor necrosis factor alpha (TNF-α), interleukin 1 (IL-1), or interleukin 17 (IL-17).
- High quality
- Low endotoxin
- Affordable
The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways. G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouse G-CSF proteins are cross-reactive.
The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways. G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouse G-CSF proteins are cross-reactive.
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: For research use only.
3 Options Available Below
Product Details & Documents
Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte proliferation, terminal differentiation, and activation. G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, tumor necrosis factor alpha (TNF-α), interleukin 1 (IL-1), or interleukin 17 (IL-17).
- High quality
- Low endotoxin
- Affordable
The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways. G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouse G-CSF proteins are cross-reactive.
The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways. G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouse G-CSF proteins are cross-reactive.
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: For research use only.
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- SHBT100-72-10UG
- SHBT100-72-100UG
- SHBT100-72-1MG
- Protein/peptide name:
- G-CSF
- G-CSF
- G-CSF
- Protein synonyms:
- GM-CSFβ|pluripoietin|MGI-1G|CSF-3
- GM-CSFβ|pluripoietin|MGI-1G|CSF-3
- GM-CSFβ|pluripoietin|MGI-1G|CSF-3
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Protein function:
- Cytokine
- Cytokine
- Cytokine
- Species:
- Human
- Human
- Human
- Source:
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- P09919
- P09919
- P09919
- Sequence:
- MTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQP
- MTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQP
- MTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQP
- Protease-free:
- N
- N
- N
- Animal-free:
- N
- N
- N
- Nuclease-free:
- N
- N
- N
- Carrier-free:
- Y
- Y
- Y
- Endotoxin-free:
- N
- N
- N
- Endotoxin level:
- Low
- Low
- Low
- Endotoxin content:
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- UniProtKB:
- P09919
- P09919
- P09919
- Biological activity:
- Bioactivity assay: NFS-60 cell proliferation, ED50 ≤0,060 ng/ml, bioactivity ≥1,7×10⁷ units/mg
- Bioactivity assay: NFS-60 cell proliferation, ED50 ≤0,060 ng/ml, bioactivity ≥1,7×10⁷ units/mg
- Bioactivity assay: NFS-60 cell proliferation, ED50 ≤0,060 ng/ml, bioactivity ≥1,7×10⁷ units/mg
- Purity:
- ≥95%
- ≥95%
- ≥95%
- Grade:
- RUO
- RUO
- RUO
- Formulation:
- 20 mM acetic acid, 50 mM sodium chloride
- 20 mM acetic acid, 50 mM sodium chloride
- 20 mM acetic acid, 50 mM sodium chloride
- Molecular weight:
- 18,8 kDa
- 18,8 kDa
- 18,8 kDa
- Reconstitution instructions:
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Storage conditions:
- −20 °C
- −20 °C
- −20 °C
- Shipping temperature:
- RT
- RT
- RT
- Tested applications:
- Bioassay
- Bioassay
- Bioassay
Specifications
Product Family Options
Product Information
- Pack typePkAvailabilityPrice
- Specifications:
More
Specifications
Cat. No.SHBT100-72-10UGProtein/peptide nameG-CSFProtein synonymsGM-CSFβ|pluripoietin|MGI-1G|CSF-3Protein/peptide typeRecombinantProtein functionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDP09919SequenceMTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQPProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0.1UniProtKBP09919Biological activityBioactivity assay: NFS-60 cell proliferation, ED50 ≤0,060 ng/ml, bioactivity ≥1,7×10⁷ units/mgPurity≥95%GradeRUOFormulation20 mM acetic acid, 50 mM sodium chlorideMolecular weight18,8 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions−20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-72-100UGProtein/peptide nameG-CSFProtein synonymsGM-CSFβ|pluripoietin|MGI-1G|CSF-3Protein/peptide typeRecombinantProtein functionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDP09919SequenceMTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQPProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0.1UniProtKBP09919Biological activityBioactivity assay: NFS-60 cell proliferation, ED50 ≤0,060 ng/ml, bioactivity ≥1,7×10⁷ units/mgPurity≥95%GradeRUOFormulation20 mM acetic acid, 50 mM sodium chlorideMolecular weight18,8 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions−20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-72-1MGProtein/peptide nameG-CSFProtein synonymsGM-CSFβ|pluripoietin|MGI-1G|CSF-3Protein/peptide typeRecombinantProtein functionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDP09919SequenceMTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQPProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0.1UniProtKBP09919Biological activityBioactivity assay: NFS-60 cell proliferation, ED50 ≤0,060 ng/ml, bioactivity ≥1,7×10⁷ units/mgPurity≥95%GradeRUOFormulation20 mM acetic acid, 50 mM sodium chlorideMolecular weight18,8 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions−20 °CShipping temperatureRTTested applicationsBioassay