Human Recombinant PDGF-AA (from E. coli)
About this item
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.
- High quality
- Low endotoxin
- Affordable
PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.
These research grade recombinant proteins are typically used as cytokines, growth factors and chemokines in cell based assays and cell culture.
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: For research use only.
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Product Details & Documents
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.
- High quality
- Low endotoxin
- Affordable
PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.
These research grade recombinant proteins are typically used as cytokines, growth factors and chemokines in cell based assays and cell culture.
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: For research use only.
Documents
Certificates
Search by Lot NumberSpecifications for Product Family
Specifications
Specifications
- Catalog No:
- SHBT100-16-10UG
- SHBT100-16-100UG
- SHBT100-16-1MG
- Protein/peptide name:
- PDGF-AA
- PDGF-AA
- PDGF-AA
- Protein synonyms:
- ODGF|GDGF
- ODGF|GDGF
- ODGF|GDGF
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Protein function:
- Growth factor
- Growth factor
- Growth factor
- Species:
- Human
- Human
- Human
- Source:
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- P04085
- P04085
- P04085
- Sequence:
- MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT
- MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT
- MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT
- Protease-free:
- N
- N
- N
- Animal-free:
- N
- N
- N
- Nuclease-free:
- N
- N
- N
- Carrier-free:
- Y
- Y
- Y
- Endotoxin-free:
- N
- N
- N
- Endotoxin level:
- Low
- Low
- Low
- Endotoxin content:
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- UniProtKB:
- P04085
- P04085
- P04085
- Biological activity:
- Bioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
- Bioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
- Bioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
- Purity:
- ≥95%
- ≥95%
- ≥95%
- Grade:
- RUO
- RUO
- RUO
- Formulation:
- 0,1% Trifluoroacetic Acid (TFA)
- 0,1% Trifluoroacetic Acid (TFA)
- 0,1% Trifluoroacetic Acid (TFA)
- Molecular weight:
- 14,4/28,9 (kDa)
- 14,4/28,9 (kDa)
- 14,4/28,9 (kDa)
- Reconstitution instructions:
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Storage conditions:
- −20 °C
- −20 °C
- −20 °C
- Shipping temperature:
- RT
- RT
- RT
- Tested applications:
- Bioassay
- Bioassay
- Bioassay
Specifications
Product Family Options
Product Information
- Pack typePkAvailabilityPrice
- Specifications:
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Specifications
Cat. No.SHBT100-16-10UGProtein/peptide namePDGF-AAProtein synonymsODGF|GDGFProtein/peptide typeRecombinantProtein functionGrowth factorSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDP04085SequenceMSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPTProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0.1UniProtKBP04085Biological activityBioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mgPurity≥95%GradeRUOFormulation0,1% Trifluoroacetic Acid (TFA)Molecular weight14,4/28,9 (kDa)Reconstitution instructionsSterile water at 0,1 mg/mlStorage conditions−20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-16-100UGProtein/peptide namePDGF-AAProtein synonymsODGF|GDGFProtein/peptide typeRecombinantProtein functionGrowth factorSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDP04085SequenceMSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPTProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0.1UniProtKBP04085Biological activityBioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mgPurity≥95%GradeRUOFormulation0,1% Trifluoroacetic Acid (TFA)Molecular weight14,4/28,9 (kDa)Reconstitution instructionsSterile water at 0,1 mg/mlStorage conditions−20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-16-1MGProtein/peptide namePDGF-AAProtein synonymsODGF|GDGFProtein/peptide typeRecombinantProtein functionGrowth factorSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDP04085SequenceMSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPTProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0.1UniProtKBP04085Biological activityBioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mgPurity≥95%GradeRUOFormulation0,1% Trifluoroacetic Acid (TFA)Molecular weight14,4/28,9 (kDa)Reconstitution instructionsSterile water at 0,1 mg/mlStorage conditions−20 °CShipping temperatureRTTested applicationsBioassay