Mouse Recombinant IL-21 (from E. coli)
About this item
Interleukin 21 (IL-21) is a member of the common-gamma chain family of cytokines that are involved in immunoregulation. IL-21 is normally expressed by activated CD4+ T cells. The IL-21 receptor (IL-21R) activates the JAK/STAT signaling pathway and is expressed on T, B, and natural killer (NK) cells. Within the B cell lineage, IL-21 is a switch factor regulating IgG1 and IgG3 antibody production. IL-21 also cooperates with interleukin 4 (IL-4) for the production of multiple antibody classes in B cells. IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, NK, and dendritic cells.
- High Quality
- Low Endotoxin
- Affordable
A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.
Caution: For research use only.
4 Options Available Below
Product Details & Documents
Interleukin 21 (IL-21) is a member of the common-gamma chain family of cytokines that are involved in immunoregulation. IL-21 is normally expressed by activated CD4+ T cells. The IL-21 receptor (IL-21R) activates the JAK/STAT signaling pathway and is expressed on T, B, and natural killer (NK) cells. Within the B cell lineage, IL-21 is a switch factor regulating IgG1 and IgG3 antibody production. IL-21 also cooperates with interleukin 4 (IL-4) for the production of multiple antibody classes in B cells. IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, NK, and dendritic cells.
- High Quality
- Low Endotoxin
- Affordable
A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.
Caution: For research use only.
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- SHBT200-70-10UG
- SHBT200-70-100UG
- SHBT200-70-500UG
- SHBT200-70-1MG
- Protein/peptide name:
- IL-21
- IL-21
- IL-21
- IL-21
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein function:
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Species:
- Mouse
- Mouse
- Mouse
- Mouse
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- Q9ES17
- Q9ES17
- Q9ES17
- Q9ES17
- Sequence:
- MHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLS
- MHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLS
- MHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLS
- MHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLS
- Protease-free:
- N
- N
- N
- N
- Animal-free:
- N
- N
- N
- N
- Nuclease-free:
- N
- N
- N
- N
- Carrier-free:
- Y
- Y
- Y
- Y
- Endotoxin-free:
- N
- N
- N
- N
- Endotoxin level:
- Low
- Low
- Low
- Low
- Endotoxin content:
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Biological activity:
- Bioactivity assay: proliferation of B9 cells, ED50 ≤20 ng/ml, Bioactivity ≥1,0×10⁵ units/mg or 5,0×10⁴ units/mg
- Bioactivity assay: proliferation of B9 cells, ED50 ≤20 ng/ml, Bioactivity ≥1,0×10⁵ units/mg or 5,0×10⁴ units/mg
- Bioactivity assay: proliferation of B9 cells, ED50 ≤20 ng/ml, Bioactivity ≥1,0×10⁵ units/mg or 5,0×10⁴ units/mg
- Bioactivity assay: proliferation of B9 cells, ED50 ≤20 ng/ml, Bioactivity ≥1,0×10⁵ units/mg or 5,0×10⁴ units/mg
- Purity:
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- Grade:
- RUO
- RUO
- RUO
- RUO
- Formulation:
- 20 mM sodium bicarbonate, pH 8,5
- 20 mM sodium bicarbonate, pH 8,5
- 20 mM sodium bicarbonate, pH 8,5
- 20 mM sodium bicarbonate, pH 8,5
- Molecular weight:
- 15,1 kDa
- 15,1 kDa
- 15,1 kDa
- 15,1 kDa
- Reconstitution instructions:
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Storage conditions:
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- Shipping temperature:
- RT
- RT
- RT
- RT
- Tested applications:
- Bioassay
- Bioassay
- Bioassay
- Bioassay
Specifications
Product Family Options
Product Information
- Pack typePkAvailabilityPrice
- Specifications:
More
Specifications
Cat. No.SHBT200-70-10UGProtein/peptide nameIL-21Protein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDQ9ES17SequenceMHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLSProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity assay: proliferation of B9 cells, ED50 ≤20 ng/ml, Bioactivity ≥1,0×10⁵ units/mg or 5,0×10⁴ units/mgPurity≥95%GradeRUOFormulation20 mM sodium bicarbonate, pH 8,5Molecular weight15,1 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT200-70-100UGProtein/peptide nameIL-21Protein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDQ9ES17SequenceMHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLSProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity assay: proliferation of B9 cells, ED50 ≤20 ng/ml, Bioactivity ≥1,0×10⁵ units/mg or 5,0×10⁴ units/mgPurity≥95%GradeRUOFormulation20 mM sodium bicarbonate, pH 8,5Molecular weight15,1 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT200-70-500UGProtein/peptide nameIL-21Protein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDQ9ES17SequenceMHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLSProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity assay: proliferation of B9 cells, ED50 ≤20 ng/ml, Bioactivity ≥1,0×10⁵ units/mg or 5,0×10⁴ units/mgPurity≥95%GradeRUOFormulation20 mM sodium bicarbonate, pH 8,5Molecular weight15,1 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT200-70-1MGProtein/peptide nameIL-21Protein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDQ9ES17SequenceMHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLSProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity assay: proliferation of B9 cells, ED50 ≤20 ng/ml, Bioactivity ≥1,0×10⁵ units/mg or 5,0×10⁴ units/mgPurity≥95%GradeRUOFormulation20 mM sodium bicarbonate, pH 8,5Molecular weight15,1 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay