Mouse Recombinant IL-1 B (from E. coli)
Supplier: Shenandoah Biotechnology
About this item
Interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine that is produced by monocytes, macrophages, and dendritic cells (DCs). IL-1β signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1β and the independently regulated IL-1α protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.
- High quality
- Low endotoxin
- Affordable
: For research use only.
4 Options Available Below
Product Details & Documents
Interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine that is produced by monocytes, macrophages, and dendritic cells (DCs). IL-1β signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1β and the independently regulated IL-1α protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.
- High quality
- Low endotoxin
- Affordable
: For research use only.
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- SHBT200-68-10UG
- SHBT200-68-100UG
- SHBT200-68-500UG
- SHBT200-68-1MG
- Protein/peptide name:
- IL-1 B
- IL-1 B
- IL-1 B
- IL-1 B
- Protein synonyms:
- EP|Catabolin|LAF|LEM|MCF
- EP|Catabolin|LAF|LEM|MCF
- EP|Catabolin|LAF|LEM|MCF
- EP|Catabolin|LAF|LEM|MCF
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein function:
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Species:
- Mouse
- Mouse
- Mouse
- Mouse
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- P10749
- P10749
- P10749
- P10749
- Sequence:
- MVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS
- MVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS
- MVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS
- MVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS
- Protease-free:
- N
- N
- N
- N
- Animal-free:
- N
- N
- N
- N
- Nuclease-free:
- N
- N
- N
- N
- Carrier-free:
- Y
- Y
- Y
- Y
- Endotoxin-free:
- N
- N
- N
- N
- Endotoxin level:
- Low
- Low
- Low
- Low
- Endotoxin content:
- Endotoxin LAL (EU/µg) ≤1
- Endotoxin LAL (EU/µg) ≤1
- Endotoxin LAL (EU/µg) ≤1
- Endotoxin LAL (EU/µg) ≤1
- Biological activity:
- Bioactivity Assay: D10S cell proliferation, ED₅₀ ≤0,015 ng/ml, Bioactivity ≥6,7×10⁷ untis/mg
- Bioactivity Assay: D10S cell proliferation, ED₅₀ ≤0,015 ng/ml, Bioactivity ≥6,7×10⁷ untis/mg
- Bioactivity Assay: D10S cell proliferation, ED₅₀ ≤0,015 ng/ml, Bioactivity ≥6,7×10⁷ untis/mg
- Bioactivity Assay: D10S cell proliferation, ED₅₀ ≤0,015 ng/ml, Bioactivity ≥6,7×10⁷ untis/mg
- Purity:
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- Grade:
- RUO
- RUO
- RUO
- RUO
- Formulation:
- 10 mM Sodium phosphate, pH 7,5
- 10 mM Sodium phosphate, pH 7,5
- 10 mM Sodium phosphate, pH 7,5
- 10 mM Sodium phosphate, pH 7,5
- Molecular weight:
- 17,5 kDa
- 17,5 kDa
- 17,5 kDa
- 17,5 kDa
- Reconstitution instructions:
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Storage conditions:
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- Shipping temperature:
- RT
- RT
- RT
- RT
- Tested applications:
- Bioassay
- Bioassay
- Bioassay
- Bioassay
Specifications
Product Family Options
Product Information
- Pack typePkAvailabilityPrice
- Specifications:
More
Specifications
Cat. No.SHBT200-68-10UGProtein/peptide nameIL-1 BProtein synonymsEP|Catabolin|LAF|LEM|MCFProtein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP10749SequenceMVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSSProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤1Biological activityBioactivity Assay: D10S cell proliferation, ED₅₀ ≤0,015 ng/ml, Bioactivity ≥6,7×10⁷ untis/mgPurity≥95%GradeRUOFormulation10 mM Sodium phosphate, pH 7,5Molecular weight17,5 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT200-68-100UGProtein/peptide nameIL-1 BProtein synonymsEP|Catabolin|LAF|LEM|MCFProtein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP10749SequenceMVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSSProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤1Biological activityBioactivity Assay: D10S cell proliferation, ED₅₀ ≤0,015 ng/ml, Bioactivity ≥6,7×10⁷ untis/mgPurity≥95%GradeRUOFormulation10 mM Sodium phosphate, pH 7,5Molecular weight17,5 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT200-68-500UGProtein/peptide nameIL-1 BProtein synonymsEP|Catabolin|LAF|LEM|MCFProtein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP10749SequenceMVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSSProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤1Biological activityBioactivity Assay: D10S cell proliferation, ED₅₀ ≤0,015 ng/ml, Bioactivity ≥6,7×10⁷ untis/mgPurity≥95%GradeRUOFormulation10 mM Sodium phosphate, pH 7,5Molecular weight17,5 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT200-68-1MGProtein/peptide nameIL-1 BProtein synonymsEP|Catabolin|LAF|LEM|MCFProtein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP10749SequenceMVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSSProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤1Biological activityBioactivity Assay: D10S cell proliferation, ED₅₀ ≤0,015 ng/ml, Bioactivity ≥6,7×10⁷ untis/mgPurity≥95%GradeRUOFormulation10 mM Sodium phosphate, pH 7,5Molecular weight17,5 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay