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Human Recombinant PDGF-AB (from <i>E. coli</i>)

Human Recombinant PDGF-AB (from E. coli)

Supplier:   Shenandoah Biotechnology
Human Recombinant PDGF-AB (from <i>E. coli</i>)
Supplier:  Shenandoah Biotechnology
CertificatesHuman Recombinant PDGF-AB (from <i>E. coli</i>)

4 Options Available Below

Product Details & Documents

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.

  • High quality
  • Low endotoxin
  • Affordable

PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.

Delivery information: Certificate of Analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

Caution: For research use only.

Specifications for Product Family

Specifications

Specifications

  • Catalog No:
  • SHBT100-17-10UG
  • SHBT100-17-100UG
  • SHBT100-17-500UG
  • SHBT100-17-1MG
  • Protein/peptide name:
  • PDGF-AB
  • PDGF-AB
  • PDGF-AB
  • PDGF-AB
  • Protein synonyms:
  • ODGF|GDGF
  • ODGF|GDGF
  • ODGF|GDGF
  • ODGF|GDGF
  • Protein/peptide type:
  • Recombinant
  • Recombinant
  • Recombinant
  • Recombinant
  • Protein function:
  • Cytokine
  • Cytokine
  • Cytokine
  • Cytokine
  • Species:
  • Human
  • Human
  • Human
  • Human
  • Source:
  • E. coli
  • E. coli
  • E. coli
  • E. coli
  • Conjugation:
  • Unconjugated
  • Unconjugated
  • Unconjugated
  • Unconjugated
  • Gene ID:
  • P04085/P01127
  • P04085/P01127
  • P04085/P01127
  • P04085/P01127
  • Sequence:
  • Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
  • Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
  • Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
  • Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
  • Protease-free:
  • N
  • N
  • N
  • N
  • Animal-free:
  • N
  • N
  • N
  • N
  • Nuclease-free:
  • N
  • N
  • N
  • N
  • Carrier-free:
  • Y
  • Y
  • Y
  • Y
  • Endotoxin-free:
  • N
  • N
  • N
  • N
  • Endotoxin level:
  • Low
  • Low
  • Low
  • Low
  • Endotoxin content:
  • Endotoxin LAL (EU/µg) ≤0.1
  • Endotoxin LAL (EU/µg) ≤0.1
  • Endotoxin LAL (EU/µg) ≤0.1
  • Endotoxin LAL (EU/µg) ≤0.1
  • UniProtKB:
  • P04085/P01127
  • P04085/P01127
  • P04085/P01127
  • P04085/P01127
  • Biological activity:
  • Bioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤20 ng/ml, bioactivity ≥5,0×10⁴ units/mg
  • Bioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤20 ng/ml, bioactivity ≥5,0×10⁴ units/mg
  • Bioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤20 ng/ml, bioactivity ≥5,0×10⁴ units/mg
  • Bioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤20 ng/ml, bioactivity ≥5,0×10⁴ units/mg
  • Purity:
  • ≥95%
  • ≥95%
  • ≥95%
  • ≥95%
  • Grade:
  • RUO
  • RUO
  • RUO
  • RUO
  • Formulation:
  • 0,1% Trifluoroacetic Acid (TFA)
  • 0,1% Trifluoroacetic Acid (TFA)
  • 0,1% Trifluoroacetic Acid (TFA)
  • 0,1% Trifluoroacetic Acid (TFA)
  • Molecular weight:
  • Alpha: 14,4 kDa, beta: 12,4 kDa, total 26,8
  • Alpha: 14,4 kDa, beta: 12,4 kDa, total 26,8
  • Alpha: 14,4 kDa, beta: 12,4 kDa, total 26,8
  • Alpha: 14,4 kDa, beta: 12,4 kDa, total 26,8
  • Reconstitution instructions:
  • Sterile water at 0,1 mg/ml
  • Sterile water at 0,1 mg/ml
  • Sterile water at 0,1 mg/ml
  • Sterile water at 0,1 mg/ml
  • Storage conditions:
  • −20 °C
  • −20 °C
  • −20 °C
  • −20 °C
  • Shipping temperature:
  • RT
  • RT
  • RT
  • RT
  • Tested applications:
  • Bioassay
  • Bioassay
  • Bioassay
  • Bioassay

Specifications

Product Family Options

Product Information

  • Pack type
    Pk
    Availability
    Price
  • SHBT100-17-10UG
    Vial
    10 µG
    Log in for availability
    Log in for availability
    1 * 10 µG
    1 * 10 µG - 190,00 €
    190,00 €
    1 * 10 µG
       190,00 €
    Specifications:
    More
    Specifications
    Cat. No.
    SHBT100-17-10UG
    Protein/peptide name
    PDGF-AB
    Protein synonyms
    ODGF|GDGF
    Protein/peptide type
    Recombinant
    Protein function
    Cytokine
    Species
    Human
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    P04085/P01127
    Sequence
    Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
    Protease-free
    N
    Animal-free
    N
    Nuclease-free
    N
    Carrier-free
    Y
    Endotoxin-free
    N
    Endotoxin level
    Low
    Endotoxin content
    Endotoxin LAL (EU/µg) ≤0.1
    UniProtKB
    P04085/P01127
    Biological activity
    Bioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤20 ng/ml, bioactivity ≥5,0×10⁴ units/mg
    Purity
    ≥95%
    Grade
    RUO
    Formulation
    0,1% Trifluoroacetic Acid (TFA)
    Molecular weight
    Alpha: 14,4 kDa, beta: 12,4 kDa, total 26,8
    Reconstitution instructions
    Sterile water at 0,1 mg/ml
    Storage conditions
    −20 °C
    Shipping temperature
    RT
    Tested applications
    Bioassay
  • SHBT100-17-100UG
    Vial
    100 µG
    Log in for availability
    Log in for availability
    1 * 100 µG
    1 * 100 µG - 539,00 €
    539,00 €
    1 * 100 µG
       539,00 €
    Specifications:
    More
    Specifications
    Cat. No.
    SHBT100-17-100UG
    Protein/peptide name
    PDGF-AB
    Protein synonyms
    ODGF|GDGF
    Protein/peptide type
    Recombinant
    Protein function
    Cytokine
    Species
    Human
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    P04085/P01127
    Sequence
    Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
    Protease-free
    N
    Animal-free
    N
    Nuclease-free
    N
    Carrier-free
    Y
    Endotoxin-free
    N
    Endotoxin level
    Low
    Endotoxin content
    Endotoxin LAL (EU/µg) ≤0.1
    UniProtKB
    P04085/P01127
    Biological activity
    Bioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤20 ng/ml, bioactivity ≥5,0×10⁴ units/mg
    Purity
    ≥95%
    Grade
    RUO
    Formulation
    0,1% Trifluoroacetic Acid (TFA)
    Molecular weight
    Alpha: 14,4 kDa, beta: 12,4 kDa, total 26,8
    Reconstitution instructions
    Sterile water at 0,1 mg/ml
    Storage conditions
    −20 °C
    Shipping temperature
    RT
    Tested applications
    Bioassay
  • SHBT100-17-500UG
    Vial
    500 µG
    Log in for availability
    Log in for availability
    1 * 500 µG
    1 * 500 µG - 2 660,00 €
    2 660,00 €
    1 * 500 µG
       2 660,00 €
    Specifications:
    More
    Specifications
    Cat. No.
    SHBT100-17-500UG
    Protein/peptide name
    PDGF-AB
    Protein synonyms
    ODGF|GDGF
    Protein/peptide type
    Recombinant
    Protein function
    Cytokine
    Species
    Human
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    P04085/P01127
    Sequence
    Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
    Protease-free
    N
    Animal-free
    N
    Nuclease-free
    N
    Carrier-free
    Y
    Endotoxin-free
    N
    Endotoxin level
    Low
    Endotoxin content
    Endotoxin LAL (EU/µg) ≤0.1
    UniProtKB
    P04085/P01127
    Biological activity
    Bioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤20 ng/ml, bioactivity ≥5,0×10⁴ units/mg
    Purity
    ≥95%
    Grade
    RUO
    Formulation
    0,1% Trifluoroacetic Acid (TFA)
    Molecular weight
    Alpha: 14,4 kDa, beta: 12,4 kDa, total 26,8
    Reconstitution instructions
    Sterile water at 0,1 mg/ml
    Storage conditions
    −20 °C
    Shipping temperature
    RT
    Tested applications
    Bioassay
  • SHBT100-17-1MG
    Vial
    1 mg
    Log in for availability
    Log in for availability
    1 * 1 mg
    1 * 1 mg - 4 440,00 €
    4 440,00 €
    1 * 1 mg
       4 440,00 €
    Specifications:
    More
    Specifications
    Cat. No.
    SHBT100-17-1MG
    Protein/peptide name
    PDGF-AB
    Protein synonyms
    ODGF|GDGF
    Protein/peptide type
    Recombinant
    Protein function
    Cytokine
    Species
    Human
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    P04085/P01127
    Sequence
    Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
    Protease-free
    N
    Animal-free
    N
    Nuclease-free
    N
    Carrier-free
    Y
    Endotoxin-free
    N
    Endotoxin level
    Low
    Endotoxin content
    Endotoxin LAL (EU/µg) ≤0.1
    UniProtKB
    P04085/P01127
    Biological activity
    Bioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤20 ng/ml, bioactivity ≥5,0×10⁴ units/mg
    Purity
    ≥95%
    Grade
    RUO
    Formulation
    0,1% Trifluoroacetic Acid (TFA)
    Molecular weight
    Alpha: 14,4 kDa, beta: 12,4 kDa, total 26,8
    Reconstitution instructions
    Sterile water at 0,1 mg/ml
    Storage conditions
    −20 °C
    Shipping temperature
    RT
    Tested applications
    Bioassay