Anti-RIG-I Rabbit Polyclonal Antibody
Catalog # ENZOALX210932C100
Supplier: ENZO LIFE SCIENCES
Specifications
- Antibody type:Primary
- Antigen name:Retinoic Acid-inducible Gene 1
- Antigen symbol:RIG-1
- Clonality:Polyclonal
- Host:Rabbit
- ImmunoPrecipitation:Yes
- Western blot:Yes
- Seq:02
- Form:Liquid. In PBS containing 0,02% sodium azide.
- Antigen synonyms:Probable ATP-dependent RNA helicase DDX58|Retinoic acid-inducible gene 1 protein|DEAD-box protein 58|RIGI|RIG-I|SGMRT2|RLR-1
- Concentration:1 mg/ml
- Purification:Protein A-affinity purified
- Pk:100 µG
Specifications
About this item
RIG-I (retinoic acid-inducible gene I; Ddx58), a member of the DEAD-box RNA helicases, is activated by cytoplasmic dsRNA and 5’-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-1 recruits the CARD adaptor inducing IFN-β (Cardif) in a CARD-CARD-dependent manner resulting in NF-κB and IRF3 activation.
- For Immunoprecipitation, Western Blot
Recognizes human RIG-I.
Type: Primary
Antigen: RIG-I
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human