Mouse recombinant DLL4 (from HEK293 cells)
Catalog # PRSI90-154
Supplier: ProSci Inc.
CAS Number:
Specifications
- Pk:10 µG
- Protein/peptide type:Recombinant
- Source:HEK293 cells
- Species:Mouse
- Environmentally Preferable:
- Tag sequence:Fc Tag
- Storage conditions:Working aliquots are stable for up to 3 months when stored at −20 °C.
- Biological activity:Inhibits adipogenesis of 3T3L-1 cells.
- Protein synonyms:Delta4|Delta-like Protein 4
- Protein/peptide name:DLL4
- Purity:>90% (SDS-PAGE)
- Sequence:1-532
- Formulation:0.2um-filtered solution in PBS.
Specifications
About this item
The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signalling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
Fusion-Tag: Fc Tag
This recombinant proteins is for research use only.