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Human Recombinant EDF1 (from E. coli)

50 µG
Catalog # PRSI91-979
Supplier:   ProSci Inc.
Human Recombinant EDF1 (from <i>E. coli</i>)
Catalog # PRSI91-979
Supplier:  ProSci Inc.
CAS Number:  
Human Recombinant EDF1 (from E. coli)

50 µG

Specifications
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Specifications
CAS Number:  
Price
730,00 €
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1 * 50 µG
Product Details & Documents

Endothelial Differentiation-Related Factor 1 (EDF1) is a 148 amino acid transcriptional coactivator that contains 1 HTH cro/C1-type DNA-binding domain. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. When endothelial cells are induced to differentiate in vitro, EDF1 is downregulated, leading to inhibition of cell growth and cell polarization. EDF1 binds calmodulin thorough its IQ domain and regulates nitric oxide synthase activity through calmodulin sequestration in the cytoplasm. Though ubiquitously expressed, EDF1 is most abundant in adult liver, heart, adipose tissues, intestine and pancreas. In fetal tissues, EDF1 is most abundant in kidney. There are two isoforms of EDF1 that are produced as a result of alternative splicing events.

  • This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag

 

Specifications

Specifications

  • Pk:
    50 µG
  • Protein/peptide name:
    EDF1
  • Protein synonyms:
    Endothelial Differentiation-Related Factor 1|EDF1|MBF1|EDF-1|Multiprotein-Bridging Factor 1
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Sequence:
    Ala2-Lys148
  • Source:
    E. coli
  • Molecular weight:
    17.4 kD
  • Cat. No.:
    PRSI91-979
  • Protein/peptide type:
    Recombinant
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tag sequence:
    C-6 His tag
  • Tested applications:
    Bioassay
  • Species:
    Human

Specifications