Human recombinant Cornulin (from E. coli)
PRSI91-100
:
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Tag sequence:N-6 His tag
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:Tumor-Related Protein|DRC1|53 kDa Squamous Epithelial-Induced Stress Protein|C1orf10|SEP53|Squamous Epithelial Heat Shock Protein 53|PDRC1|53 kDa Putative Calcium-Binding Protein|Cornulin|CRNN|58 kDa Heat Shock Protein
- Protein/peptide name:Cornulin
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:17.45 kD
- Sequence:Met1-Ser140
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When Cornulin is overexpressed in oral squamous carcinoma cell lines, it regulates negatively cell proliferation by the induction of G1 arrest.
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: N-6 His tag