Order Entry
Export
ContactUsLinkComponent
Anti-DDX58 Mouse Monoclonal Antibody (Biotin) [clone: Alme-1]
Anti-DDX58 Mouse Monoclonal Antibody (Biotin) [clone: Alme-1]
Catalog # PRSI36-103
Supplier:  ProSci Inc.
undefined
Anti-DDX58 Mouse Monoclonal Antibody (Biotin) [clone: Alme-1]
Catalog # PRSI36-103
Supplier:  ProSci Inc.

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
  • Antigen symbol:
    DDX58
  • Clonality:
    Monoclonal
  • Clone:
    Alme-1
  • Conjugation:
    Biotin
  • Host:
    Mouse
  • ImmunoChemistry:
    Yes
  • ImmunoPrecipitation:
    Yes
  • Isotype:
    IgG1
  • Reactivity:
    Human,
    Mouse
  • Western blot:
    Yes
  • Form:
    Liquid
  • Gene ID:
    23586
  • Antigen synonyms:
    Probable ATP-dependent RNA Helicase DDX58|DEAD-box Protein 58|RIG-1|Retinoic Acid-inducible Gene 1 Protein
  • Storage buffer:
    In PBS containing 0.02% sodium azide.
  • Storage temperature:
    Stable for at least 1 year after receipt when stored at -20˚C.
  • Concentration:
    0.5 mg/ml
  • Shipping temperature:
    -20°C
  • Immunogen:
    Recombinant human RIG-I (aa 201-713).
  • Purification:
    >95% (SDS-PAGE)
  • Size:
    100 μg
  • Pk:
    100 µG

Specifications

About this item

RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5’-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-I recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.

Type: Primary
Antigen: DDX58
Clonality: Monoclonal
Clone: Alme-1
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse