Anti-MET Rabbit Polyclonal Antibody
Catalog # PRSI80-020
Supplier: ProSci Inc.
Specifications
- Antibody type:Primary
- Antigen name:MET Proto-Oncogene, Receptor Tyrosine Kinase
- Antigen symbol:MET
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Form:Liquid
- Gene ID:4233
- Antigen synonyms:DFNB97|Hepatocyte Growth Factor Receptor|AUTS9|HGFR|c-Met|MET proto-oncogene|RCCP2
- Modification:phospho-Tyr1003
- Storage buffer:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Molecular weight:155 kDa
- Storage temperature:Store antibody at –20 °C for up to one year.
- Concentration:1 mg/mL
- Shipping temperature:-20°C
- Immunogen:c-Met (phospho Tyr1003) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1003 (V-D-Y (p)-R-A) derived from Human c-Met.
- Purification:Purified by affinity-chromatography using epitope-specific peptide.
- Size:100 µg
- Pk:100 µG
Specifications
About this item
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.
Western Blot: 1:500~1:1000
Type: Primary
Antigen: MET
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat