Specifications
- Antigen name:DEXH (Asp-Glu-X-His) box Polypeptide 58
- Antigen symbol:LGP2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Antigen synonyms:DEXH (Asp-Glu-X-His) box polypeptide 58 |RNA helicase LGP2 |D11LGP2 |DHX58|D11lgp2e |LGP2|ortholog of mouse D11lgp2
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:LGP2 antibody was raised against a 11 amino acid synthetic peptide from near the center of human LGP2.
- Tested applications:E, WB
- Purification:Affinity chromatography purified via peptide column
- Size:100 µg
- Pk:100 µG
Specifications
About this item
LGP2 Antibody: Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.
Type:
Antigen: LGP2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat