- Antigen name:B-cell receptor-associated protein 31
- Antigen symbol:BAP31
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Antigen synonyms:B-cell receptor-associated protein 31|DXS1357E|p28 Bap31|6C6-AG tumor-associated antigen|BCR-associated protein Bap31|CDM protein
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:BAP31 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human BAP31.
- Tested applications:E, WB, IHC
- Purification:Affinity chromatography purified via peptide column
- Size:100 µg
- Pk:100 µG
BAP31 Antibody: Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18. It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria. Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopicially, is also a potent inducer cell death.
Type:
Antigen: BAP31
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat