Specifications
- Antigen name:Angiotensin Converting Enzyme 2
- Antigen symbol:ACE2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Environmentally Preferable:
- Antigen synonyms:Angiotensin-converting enzyme homolog|ACEH|Processed angiotensin-converting enzyme 2|Angiotensin-converting enzyme 2|ACE2|ACE-related carboxypeptidase
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:ACE2 antibody was raised against a synthetic peptide corresponding to amino acids near the C-terminus of human ACE2.
- Tested applications:E, WB, IHC, IF
- Purification:Affinity chromatography purified via peptide column
- Size:100 µg
- Pk:100 µG
Specifications
About this item
ACE2 Antibody: Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.
Type:
Antigen: ACE2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human