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Anti-RIPK3 Rabbit Polyclonal Antibody
  PRSI2283
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Anti-RIPK3 Rabbit Polyclonal Antibody
  PRSI2283

 

  • Antibody type:
    Primary
  • Antigen name:
    Receptor-interacting serine/threonine-protein kinase 3
  • Antigen symbol:
    RIPK3
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • ELISA:
    Yes
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
  • Western blot:
    Yes
  • Environmentally Preferable:
  • Antigen synonyms:
    RIP-like protein kinase 3|Receptor-interacting protein 3|RIPK3|RIP-3|RIP3|Receptor-interacting serine/threonine-protein kinase 3
  • Storage buffer:
    RIP3 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Tested applications:
    E, WB, IHC, IF
  • Size:
    100 µl
  • Pk:
    100 µG

 

 

RIP3 Antibody: Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3. RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, mediates TNFR1 induced apoptosis, and attenuates RIP and TNFR1 induced NF-kappa B activation. Overexpression of RIP3 induces apoptosis and NF-kappa B activation. The messenger RNA of RIP3 is expressed in a subset of adult tissues.

RIP3 antibody was raised against a peptide corresponding to amino acids 473 to 486 of murine RIP3.

Type: Primary
Antigen: RIPK3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: 0