Complete Supplement Mixture (CSM) is a culture growth media supplement for virtually all strains of Saccharomyces cerevisiae.

• Available as single, double, triple, four, four+ dropout formulations of aminoacids
• Allows selection for auxotrophic requirements and transformants

CSM is time-tested dropout supplement for growth of S. cerevisiae. Cells grow vigorously in CSM supplemented medium which is easily made by adding the CSM powder to DOB of DOBA base medium and autoclaving.

This is used to select for yeast containing plasmids with specific nutritional markers and to select for gene function in transformation experiments.