Specifications
- Antibody type:Primary
- Antigen name:Rho Guanine Nucleotide Exchange Factor (GEF) 25
- Antigen symbol:GEFT
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 350
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:ARHGEF25|Rac/Cdc42/Rho exchange factor GEFT|ARHGP_HUMAN|RAC/CDC42 exchange factor|Guanine nucleotide exchange factor GEFT|GEFT|p63RhoGEF|RhoA/RAC/CDC42 exchange factor|p63RhoGEF |Rho guanine nucleotide exchange factor 25|RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT.
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Pk:100 µl
Specifications
About this item
GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain, heart and muscle, and weakly expressed in small intestine, colon, liver, placenta and lung. GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation. GEFT is an important regulator of processes involved in axon and dendrite formation. Involved in skeletal myogenesis, GEFT seems to be an exchange factor primarily for Rac 1 in neurons. Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: GEFT
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat