About this item
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.
Type: Primary
Antigen: PTPRC
Clonality: Monoclonal
Clone: PD7/26
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
Specifications
- Catalog No:
- BNC940472-500
- BNC940472-100
- Antigen symbol:
- PTPRC
- PTPRC
- Antigen name:
- Protein tyrosine phosphatase receptor type C
- Protein tyrosine phosphatase receptor type C
- Antigen synonyms:
- Lyt-4|Leukocyte common antigen (LCA)|CD45R|B220|T200 glycoprotein|Ly-5|GP180|Protein tyrosine phosphatase receptor type C (PTPRC)|Receptor-type tyrosine-protein phosphatase C|Loc
- Lyt-4|Leukocyte common antigen (LCA)|CD45R|B220|T200 glycoprotein|Ly-5|GP180|Protein tyrosine phosphatase receptor type C (PTPRC)|Receptor-type tyrosine-protein phosphatase C|Loc
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 594
- CF® 594
- Clone:
- Clone PD7/26
- Clone PD7/26
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 654514
- 654514
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ImmunoChemistry:
- Yes
- Yes
- ImmunoPrecipitation:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide