Analytical HPLC columns, Inertsil®

Inertsil® series phases are based on a purer, higher surface area silica which is specially manufactured to provide maximum phase coverage. The result is a series of columns which provide excellent peak shapes using simple eluents while operating at low pressure.

Inertsil® ODS-3 is used widely and reliably for long established methods in pharmaceutical, and contract research labs. It has a relatively strong retentivity compared to commercially available ODS columns.
Inertsil® ODS-3V offers all of the outstanding chromatographic benefits of Inertsil® ODS-3 with the added benefit of a more thoroughly documented, validated QC procedure consistent with the demands of GLP/GMP compliance. Each Inertsil® ODS-3V is delivered with a manufacturer‘s validation certificate showing the detailed results of every QA and QC step in manufacturing. The use of Inertsil® ODS-3V columns provides an extra measure of assurance of consistent performance from column to column and batch to batch. Inertsil® ODS-3V columns are also available in 3-column-sets packed with three different silica batches or a single silica batch to assist in reproducibility studies.
Inertsil® ODS-4 delivers the same extreme inertness to any type of compounds just like InertSustain C18 along with unprecedented stability under 100 % aqueous mobile phases for qualitative and quantitative analysis.

The same base silica gel and bonding technology that is used for Inertsil® ODS-3 is also employed for Inertsil® C8-3. The difference between the two phases is just the length of the hydrocarbon ligands.

Inertsil® CN-3 is a cyanopropyl bonded phase that provides pi-pi interactions offered by the triple bond in cyano groups. This column can be used for both reversed phase and normal phase separations. The column is originally shipped in a mixture of n-hexane/ ethanol.

Inertsil® PH-3 have phenyl groups directly bonded to the silica gel which provides pure reverse phase characteristics that are critical to resolving highly polar compounds like acidic and basic pharmaceuticals. The near perfect phenyl phase coverage on this material results in symmetric, narrow peaks for even the most polar compounds while using simple eluents like aqueous acetonitrile or methanol.

Inertsil® NH₂ has Aminopropyl groups bonded to silica gel. Generally Amino columns, including Inertsil® NH₂, are widely used for analysing sugar in reversed phase mode. Inertsil® NH₂ is also available in normal phase mode and shows unique selectivity.