Histones are soluble in water (10 mg/ml) or 0,5 N HCl (10 mg/ml), yielding a clear to hazy solution depending on the fraction. They are soluble in 6 M urea (4 to 10 mg/ml), but this will denature the histones.

Arginine-rich subgroup.

Commonly used for chromosome-reconstitution studies.

Suitable substrate for protein kinase C. Phosphorylation of this histone may also be suitable in other protein kinase systems.

Phosphorylation of this histone may also be suitable in other protein kinase systems.