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Amphotericin B

Amphotericin B

Amphotericin B
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Amphotericin B

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Amphotericin B, antifungal activity has been used against leishmaniasis caused by protozoan parasites of the Leishmania genus.

  • Moisture and light sensitive

Amphotericin B trihydrate was observed to cause suppression of bone marrow progenitor cells and to induce Actinomycin D(CR001) sensitivity in drug resistant HELA cells in vitro.

Yellow powder

Soluble in aqueous buffers at pH 2.0 or 11.0. Insoluble at pH 6.0-7.0. Also soluble in DMSO or DMF

Synonyms:  (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
  • CAS Number:1397-89-3
  • Formula:C₄₇H₇₃NO₁₇
  • MDL Number:MFCD00877763
  • Molecular Weight:924.08 g/mol
  • Merck Index:14,585
  • Storage Temperature:Refrigerator
  • EINECS:215-742-2
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