Anti-RNF144B Rabbit Polyclonal Antibody
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.Tissue specificity: Broadly expressed, with lowest levels in brain and thymus, and highest levels detectable in heart, ovary and testis.
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Type: Primary
Antigen: RNF144B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
- Size:100 μg
- Western blot:Yes
- Clonality:Polyclonal
- Purification:Purified by Protein A.
- Antibody type:Primary
- Form:liquid
- Isotype:IgG
- Host:Rabbit
- Concentration:1 ug/ul
- Shipping temperature:4 °C
- Antigen name:Ring Finger Protein 144B
- Cat. No.:BOSSBS-7613R
- Reactivity:Human|Rat|Mouse
- Gene ID:255488
- Antigen synonyms:p53RFP|IBRDC2|PIR2|bA528A10.3
- ImmunoChemistry:Yes
- Conjugation:Unconjugated
- Antigen symbol:RNF144B
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.