Anti-FAS Rabbit Polyclonal Antibody
Catalog # BOSSBS-5324R
Supplier: Bioss
Specifications
- Antibody type:Primary
- Antigen name:Fatty Acid Synthase
- Antigen symbol:FAS
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Environmentally Preferable:
- Form:liquid
- Gene ID:355
- Antigen synonyms:FASTM|APO-1|ALPS1A|TNFRSF6|CD95|APT1|FAS1
- Modification:Tyr232
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
- Concentration:1 ug/ul
- Shipping temperature:4 °C
- Immunogen:210-240/335
- Purification:Purified by Protein A.
- Size:100 μg
- Pk:100 µl
Specifications
About this item
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Type: Primary
Antigen: CD95
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human