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Anti-GNA15 Rabbit Polyclonal Antibody
Catalog # BOSSBS-13248R
Supplier:  Bioss
Anti-GNA15 Rabbit Polyclonal Antibody
Catalog # BOSSBS-13248R
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    Guanine Nucleotide Binding Protein Alpha 15
  • Antigen symbol:
    GNA15
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western blot:
    Yes
  • Form:
    liquid
  • Gene ID:
    2769
  • Antigen synonyms:
    G Protein alpha 16|GNA16
  • Storage buffer:
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
  • Concentration:
    1 ug/ul
  • Shipping temperature:
    4 °C
  • Purification:
    Purified by Protein A.
  • Size:
    100 μg
  • Pk:
    100 µl

Specifications

About this item

Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Type: Primary
Antigen: G protein alpha 16
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat