Endomorphins 1 and 2 are endogenous opioid peptides which have the highest affinity for the mu-opioid receptors. Located in various parts of the brain and interacts with mu-opioid receptors and produces analgesia.

Antibody recognizes endomorphin 1 by native applications. A dilution of 5-10 µg/ml is recommended for immunohistochemistry using formalin fixed and paraffin embedded tissues and for 4% paraformaldehyde fixed frozen tissues. A dilution of 5-15 µg/ml is recommended for immunofluorescence. Biosensis recommends optimal dilutions/concentrations should be determined by the end user. Cross-reactivity Human; mouse; rat. Endomorphin-1 is highly conserved so cross-reactivity with other species is expected. Cross-reactivity with other opioid peptides is as follows: with Endomorphin-2 <5%; Met-enkephalin <0.03%; with Leu-enkephalin 0.01%; with beta-endorphin<0.1%
Application Information:
A dilution of 5-10 µg/ml is recommended for immunohistochemistry using formalin fixed and paraffin embedded tissues and for 4% paraformaldehyde fixed frozen tissues. A dilution of 5-15 µg/ml is recommended for immunofluorescence. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: Endomorphin-1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: (YPWF) peptide
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat