Cation exchange chromatography columns, HiTrap™ Capto™ S

HiTrap Capto S chromatography column is prepacked with a strong cation exchange modern resin for small scale protein purification.

• Suitable for screening of selectivity, binding and elution conditions, and small-scale purifications
• Sulfoethyl (S) strong cation exchanger
• Optimized for capture and intermediate protein purification
• Convenient HiTrap format for easy connection to a syringe, peristaltic pump, or chromatography system such as an ÄKTA system

Capto S resin couples a sulfoethyl strong cation exchanger to a chemically modified, high-flow agarose matrix. The rigid agarose matrix provides greater particle rigidity without compromising pore size, which allows for high bed volume and purification of viscous samples at high flow rates.

High dynamic binding capacity is achieved with a dextran surface extender that coats the agarose matrix. The resin’s high binding capacity, high flow rate, and low back pressure reduce process cycle times and improve productivity at process scale.