You searched for: CGP 74514A

Supplier: Enzo Life Sciences

Cell permeable, potent and selective inhibitor of CDK1/cyclin B (IC50=25 nm). Reported to affect the activities of other kinases only at much higher concentrations: PKCα (IC50=6.1 nm), PKA (IC50=125 µm) and EGFR (IC50>10 µm). Induces mitochondrial damage and apoptosis in several human leukemia cell lines (>3 µm).