Perfectly balanced mAb formulation
Achieve perfect balance in mAb formulation with tailored excipients and fluid handling systems from Avantor.® Our cGMP-grade materials ensure monoclonal antibody stability and viscosity control while minimizing risks throughout your biopharma manufacturing process. Our scalable solutions enhance manufacturing efficiency and help you optimize final formulation and fill-finish steps. With seamless supply chain security and regulatory compliance, Avantor supports your efforts to streamline production while maintaining product quality and process safety.
We can help tailor fluid handling for optimum final formulation
Avantor’s technical specialists help you optimize fluid handling in the final formulation to enhance efficiency, prevent cross-contamination during fluid transfer and minimize the risk of product loss during sampling.
Ensure a reliable supply chain for a consistent and scalable formulation
You can meet raw material supply challenges with Avantor’s reliable, high-quality excipients, buffers, and salts. We continue to expand our manufacturing capacity to better provide the critical materials you need precisely when needed. Securing your supply chain helps you maintain consistency and balance in your formulation process and ensures product quality and scalability in biopharma production.
Ensure consistent quality and minimize risk with reliable raw materials
Ensure the safety and efficacy of your final drug product with Avantor’s high-quality, multi-compendial excipients, buffers and salts. Our raw materials consistently meet regulatory standards and are supported by globally aligned quality systems and a transparent supply chain. Our commitment to quality provides peace of mind, ensuring reliable performance and maintaining the integrity of your biopharma production process.
Get a free sample of amino acid
Request a free sample of J.T.Baker® cGMP amino acids today to experience the quality that helps de-risk your supply chain. Sourced in the U.S., these high-purity amino acids provide reliable performance for biopharma applications, ensuring compliance and consistency in your production process.
Pre-use post-sterilization integrity testing (PUPSIT)
Learn everything you should know about PUPSIT and how Avantor can guide you through the complexities of sterile filtration. Our experts can help you ensure compliance and efficiency in your biopharma processes.
Our Quality Promise
Avantor’s globally consistent quality systems offer proactive risk management through process validation, change management control and reliable, cost-effective supplier audits. Our commitment to continuous improvement eases your quality concerns and gives comprehensive regulatory support and total supply chain transparency. With our solutions, you can ensure consistent product quality, reduce risks, and maintain regulatory compliance in your biopharma processes.
Our consultative approach
At Avantor’s global Innovation Centers our scientists specialize in mAb formulation development, helping you balance stability and viscosity for optimal results. Our technical engineers design customized fluid handling systems and aseptic sampling solutions to prevent cross-contamination and product loss. With our expertise, you can ensure an efficient and contamination-free final formulation process, enhancing product quality and reducing risk.
Our Global Footprint
Partner with Avantor for global supply chain resilience supported by local expertise. Our expanding network of manufacturing sites ensures a consistent supply of critical raw materials, hydration solutions, single-use components, and fluid handling solutions, all aligned with global quality standards. With Avantor, you gain reliable access to essential products, strengthening your biopharma operations and minimizing supply disruptions.
You’ll learn to overcome the complex formulation challenges that can delay or derail the commercialization of breakthrough mAbs. This article explores the latest research on excipients, buffer composition and key manufacturing considerations to develop stable, patient-friendly monoclonal antibodies (mAbs). Learn how optimizing these factors can enhance drug stability and accelerate commercialization in the competitive biopharma landscape.
As single-use systems (SUS) rapidly expand in global drug production, manufacturers face significant risks if they underestimate manufacturing and quality requirements or regulatory compliance. Drug producers with multiple locations must adhere to global standards to avoid disruptions and maintain product quality. Learn how to navigate these challenges and optimize your single-use system implementation for efficient and compliant biopharma manufacturing.
Achieving the right balance of excipients in a custom mAb formulation is essential for producing a high-quality final product. In this article, Avantor scientists explore how amino acids and their acetyl and propionyl derivatives impact viscosity, chemical stability and protein-protein interactions. You’ll learn how optimizing these factors can enhance mAb formulation stability and improve drug performance in biopharma applications.
High-concentration mAbs pose challenges for subcutaneous injections because they can cause injection-site pain. This article compares formulations with citrate buffers against other buffers for reducing pain. It explores excipient selection strategies to mitigate risks associated with buffer composition, pH levels and viscosity. Learn how optimizing these factors can improve patient comfort and enhance the effectiveness of mAb therapies in biopharma applications.
