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Human Recombinant FGF-8B

Human Recombinant FGF-8B

Supplier: Stemcell Technologies

Fibroblast growth factor 8B (FGF-8B) is a member of the fibroblast growth factor (FGF) family and is an isoform of FGF-8. Cytokines in the FGF family possess broad mitogenic and cell survival activities (Folkman andamp; Klagsbrun; Kimelman andamp; Kirschner) and are involved in a variety of biological processes, including cell proliferation, differentiation, survival, and apoptosis (Folkman andamp; Klagsbrun; Klagsbrun; Rifkin andamp; Moscatelli). FGF-8B signals through FGF receptors (FGFRs) to activate PI3K and MAPK pathways. FGF-8B is broadly associated with mitogenic and cell survival activities, and regulates gastrulation, epithelial-mesenchymal transition, and later on mesenchymal to epithelial differentiation during embryonic development. FGF-8B has also been found in peripheral blood leukocytes and healthy bone marrow samples (Mattila andamp; Härkönen). FGF-8B has mitogenic effects on somatic cells in the germinal epithelium and is expressed in adult mouse ovarian cells and tissues, which suggests that it regulates maturation of oocytes and seminiferous epithelium in testis (Valve et al.).

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MesenCult™ MSC Basal Medium (Human)

MesenCult™ MSC Basal Medium (Human)

Supplier: Stemcell Technologies

Basal medium for human mesenchymal stem cells.

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Anti-CD45R (B220) Rat Monoclonal Antibody [clone: RA3-6B2] (Biotin)

Anti-CD45R (B220) Rat Monoclonal Antibody [clone: RA3-6B2] (Biotin)

Supplier: Stemcell Technologies

Rat monoclonal IgG2a antibody against human, mouse, cat CD45R (B220), biotin-conjugated.

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Anti-p63 (deltaN) Rabbit Polyclonal Antibody

Anti-p63 (deltaN) Rabbit Polyclonal Antibody

Supplier: Stemcell Technologies

Rabbit polyclonal antibody against human p63 (deltaN), unconjugated.

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EasySep™ HLA Chimerism Whole Blood Lymphoid Positive Selection Kits

EasySep™ HLA Chimerism Whole Blood Lymphoid Positive Selection Kits

Supplier: Stemcell Technologies

Column-free immunomagnetic positive selection of human CD3+ and CD19+ cells (e.g. lymphocytes) cells for HLA analysis.

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Anti-TER119 Rat Monoclonal Antibody [clone: TER-119] (APC)

Anti-TER119 Rat Monoclonal Antibody [clone: TER-119] (APC)

Supplier: Stemcell Technologies

Rat monoclonal IgG2b antibody against mouse TER119, APC-conjugated.

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STEMdiff™ Sensory Neuron Differentiation Kit

STEMdiff™ Sensory Neuron Differentiation Kit

Supplier: Stemcell Technologies

Differentiation kit for the generation of sensory neuronal precursors from human iPS cell-derived neural crest cells.

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Human Recombinant Osteopontin, His tag

Human Recombinant Osteopontin, His tag

Supplier: Stemcell Technologies

A member of the SIBLING family of glycoproteins (Rangaswami et al.), Osteopontin (OPN) functions as T-helper 1 cytokine, and plays an important role in cell signaling, migration, and activation (Weber et al., 2002). Osteopontin has been shown to regulate inflammation both in vitro and in vivo (Agnholt et al.; Kiefer et al.), and has been implicated in the pathophysiology of numerous cancers, including prostate (Thalmann et al.), lung (Chambers et al.), ovarian (Kim et al.), and breast etiologies (Weber et al., 2015). In humans, OPN is initially secreted as a 317 amino acid protein which is subject to tissue-specific post-translational modifications by glycosylation, phosphorylation, and transglutamination (Kazanecki et al.; Sodek et al.). This protein product contains a His-residue tag at the amino end of the polypeptide chain. For consistency and reproducibility across your applications, Osteopontin from STEMCELL comes lyophilised with ≥92% purity, and endotoxin levels are verified to be ≤1,0 EU/μg protein.

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EasySep™ Human Pan-DC Pre-Enrichment Kits

EasySep™ Human Pan-DC Pre-Enrichment Kits

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched human pan dendritic cells (DC)

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EasySep™ Mouse Biotin Positive Selection Kit II

EasySep™ Mouse Biotin Positive Selection Kit II

Supplier: Stemcell Technologies

Immunomagnetic positive selection of mouse cells labeled with biotinylated antibodies.

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Anti-CD73 Mouse Monoclonal Antibody [clone: AD2] (PE)

Anti-CD73 Mouse Monoclonal Antibody [clone: AD2] (PE)

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, chimpanzee CD73, PE-conjugated.

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Anti-CD4 Rat Monoclonal Antibody [clone: RM4-5]

Anti-CD4 Rat Monoclonal Antibody [clone: RM4-5]

Supplier: Stemcell Technologies

Rat monoclonal IgG2a antibody against mouse CD4, unconjugated.

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STEMdiff™ Intestinal Organoid Kit

STEMdiff™ Intestinal Organoid Kit

Supplier: Stemcell Technologies

Serum-free medium system for establishment and maintenance of human intestinal organoids from hPSCs.

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EasySep™ RBC Depletion Reagents, 10 ml

EasySep™ RBC Depletion Reagents, 10 ml

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched human leukocytes from whole blood.

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Anti-CD25 Mouse Monoclonal Antibody [clone: BC96]

Anti-CD25 Mouse Monoclonal Antibody [clone: BC96]

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD25, unconjugated.

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Anti-SSEA-5 Mouse Monoclonal Antibody [clone: 8E11] (APC)

Anti-SSEA-5 Mouse Monoclonal Antibody [clone: 8E11] (APC)

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human SSEA-5, APC-conjugated.

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