12525 Results for: "Enzo Life Sciences"

Supplier: ENZO LIFE SCIENCES

Supersensitive spin label

Supplier: ENZO LIFE SCIENCES

Cyclic hydroxylamine spin probe for in vivo, intraperitoneal and intravenous injections.

Supplier: ENZO LIFE SCIENCES

Cyclic hydroxylamine spin probe for in vivo, intraperitoneal and intravenous injections.

Supplier: Enzo Life Sciences

Host: Rabbit

Supplier: Enzo Life Sciences

Fodrin, also referred to as non-erythroid (αII-; brain) spectrin, is a tetrameric (αγ)2 actin-binding, fibrous protein, widely distributed in vertebrates, which forms part of the sub-membranous cytoskeleton within many cell types including neurons, and is particularly abundant with axons. The α-subunits of fodrins and spectrin are highly conserved phylogenetically, with the exception of human α-fodrin, which shares only 55-59% homology with erythroid-specific α-spectrins. The β-subunits of spectrin (and γ-subunits of fodrins) are species specific. The interleukin-1 converting enzyme (ICE) family of proteases has been implicated as important effectors of the apoptotic pathway, perhaps acting hierarchically in a protease cascade. Neuronal fodrin is known to be cleaved by calpain following ischaemic insult and it has been proposed that calpain and an unidentified protease play a role in the onset of neuronal death following transient forebrain ischaemia. Recently, an ICE-like protease has been implicated in the early cleavage of fodrin, producing a 150kDa fragment, proximal to CPP32 in Fas-induced and C2-ceramide mediated apoptosis. A cleavage product of α-fodrin has been proposed as a candidate autoantigen in primary Sjögren’s syndrome and α-fodrin has been shown to be the source of a so-called ‘inhibitory protein factor’ family, members of which have been shown to inhibit both GABA and ATP-dependent glutamate uptake into purified synaptic vesicles.

Supplier: Enzo Life Sciences

Host: Rabbit

Supplier: Enzo Life Sciences

Host: Rabbit

Supplier: Enzo Life Sciences

Host: Rabbit

Supplier: Enzo Life Sciences

Produced in E. coli.

Supplier: Enzo Life Sciences

Sequence derived from human/mouse dishevelled-2 [Cys+600-614]. Used to generate the rabbit polyclonal antiserum to dishevelled-2 (BML-DA4270).

Supplier: Enzo Life Sciences

Immunization and blocking peptide for Glutamic Acid Decarboxylase (GAD) antibodies (BML-GC3008 and BML-GC3108).

Supplier: Enzo Life Sciences

Prevents neurotoxicity of glutamate on neuronal cells.

Supplier: Enzo Life Sciences

Semisynthetic (from GM1).

Supplier: Enzo Life Sciences

Produced in E. coli.

Supplier: Enzo Life Sciences

PKCβ inhibitor

Supplier: Enzo Life Sciences

PTP inhibitor, PTEN Inhibitor

Supplier: Enzo Life Sciences

Caspase and granzyme inhibitor

Supplier: Enzo Life Sciences

5-HT2c inhibitor

Supplier: Enzo Life Sciences

RNA polymerase II inhibitor

Supplier: Enzo Life Sciences

Produced in E. coli.

Supplier: Enzo Life Sciences

Inhibits aminopeptidases like aminopeptidase B, leucine aminopeptidase, tripeptide aminopeptidase, aminopeptidases on the surface of mammalian cells. Does not inhibit carboxypeptidases. May be used in in vitro translation system to inhibit the aminopeptidases found in reticulocate or wheat germ lysates. Activates macrophages and T lymphocytes. Immunomodulator. Has antitumor properties and enhances not only blastogenesis and lymphocytes in vitro, but also establishes a delayed-type hypersensitivity in vivo.

Supplier: Enzo Life Sciences

L(+)-Arginine

Supplier: Enzo Life Sciences

Inhibitor of caspase-1 and -4

Supplier: Enzo Life Sciences

ß-Nicotinamide adenine dinucleotide phosphate tetrasodium salt (NADPH-Na4, reduced form)

Supplier: Enzo Life Sciences

Bcl-2 ligand

Supplier: Enzo Life Sciences

Copper(II) protoporphyrin IX free acid

Supplier: Enzo Life Sciences

TLR4 activator.

Supplier: Enzo Life Sciences

Fas ligand

Supplier: Enzo Life Sciences

Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins at the neuromuscular junction during development.

Supplier: Enzo Life Sciences

Glutathione, a major intracellular non-protein thiol, protects against free radical damage by providing reducing equivalents for several key antioxidant enzymes. In addition, glutathione acts as a scavenger of hydroxyl radicals and nascent oxygen. Elevated glutathione levels are associated with a reduced rate of illness, higher levels of self-rated health, lower cholesterol, lower body mass index, and lower blood pressure among the elderly. Glutathione provides a primary defense system for the removal of oxidants in the brain. Studies have revealed a correlation between low glutathione levels and damage to neurons that manufacture dopamine, suggesting a link to Parkinson's disease.