12524 Results for: "ENZO LIFE SCIENCES"

Supplier: ENZO LIFE SCIENCES

Spin trapping reagent

Supplier: ENZO LIFE SCIENCES

Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter.

Supplier: ENZO LIFE SCIENCES

Inhibitor of mTOR kinase selective against PI3K

Supplier: ENZO LIFE SCIENCES

Highly reactive thiol-specific spin label.

Supplier: Enzo Life Sciences

PLA2 activator

Supplier: Enzo Life Sciences

Host: Rat, Isotype: IgG2a

Supplier: Enzo Life Sciences

5,5'-Dithiobis(2-nitrobenzoic acid) (Ellmans reagent, DTNB)

Supplier: Enzo Life Sciences

4-Amino-2,2,6,6-tetramethylpiperidinooxy (4-amino-TEMPO)

Supplier: Enzo Life Sciences

Lithium chloride

Supplier: Enzo Life Sciences

Host: Mouse, Isotype: IgG2a

Supplier: Enzo Life Sciences

Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNF-R1 and Fas, two prototype members in the death receptor family. A member in the RIP kinase family was identified and designated RIP3. RIP3 contains an N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNF-R1, mediates TNF-R1 induced apoptosis, and attenuates RIP and TNF-R1 induced NF-κB activation. Overexpression of RIP3 induces apoptosis and NF-κB activation. The messenger RNA of RIP3 is expressed in a subset of adult tissues. Meanwhile RIP4 has been identified and initially characterized. These data suggest that RIP4 is involved in NF-κB and JNK signalling and that caspase-dependent processing of RIP4 may negatively regulate NF-κB-dependent pro-survival or pro-inflammatory signals.

Supplier: Enzo Life Sciences

5-Bromodeoxyoridine (BrdU) is an analog of thymidine (derivative of uridine) and can be incorporated specifically into DNA in place of thymidine. Cells can be pulse-labelled with BrdU, and those cells that are synthesizing DNA (in S-phase of the cell cycle) will incorporate BrdU into the DNA. MAb to BrdU can then be used to identify cells that undergo DNA synthesis during exposure to BrdU. The proportion of cells in S-phase of the cell cycle can be determined either by fluorescence microspcopy or by flow cytometric analysis.

Supplier: Enzo Life Sciences

Host: Rat, Isotype: IgG2a

Supplier: Enzo Life Sciences

Biosynthesis in RBL cells. Displays weak contractile activity on guinea pig parenchymal strip and ileum.

Supplier: Enzo Life Sciences

Novel leukotriene produced via the 15-LO pathway.

Supplier: Enzo Life Sciences

PKA activator.

Supplier: Enzo Life Sciences

Primary LTB4 metabolite produced by ω oxidation in PMNL retaining some chemotactic activity. ω oxidation is blocked by 17-ODYA.

Supplier: Enzo Life Sciences

Major bilary metabolite of cysteinyl leukotrienes in the rat. Approximately 100-fold less active than LTC4. Equiactive with LTE4 in guinea pig lung parenchyma assay.

Supplier: Enzo Life Sciences

Produced in E. coli. Coronavirus (SARS-CoV) nucleoprotein (aa 340-390) is fused to a His-tag.

Supplier: Enzo Life Sciences

Produced in E. coli. Coronavirus (SARS-CoV) envelope protein (aa 1-76) is fused to a His-tag.

Supplier: Enzo Life Sciences

Produced in E. coli. Contains 126/252 amino acids.

Supplier: Enzo Life Sciences

Recombinant Tick-borne encephalitis virus (TBEV) protein produced in HEK293 cells, incorporating a C-terminal mouse Fc-tag.

Supplier: Enzo Life Sciences

Produced in E. coli. Recombinant protein (aa 56-295).

Supplier: Enzo Life Sciences

Food intake modulator

Supplier: Enzo Life Sciences

V-ATPase inhibitor.

Supplier: Enzo Life Sciences

Inhibits PKA (Ki=3.0μM), PKG (Ki=5.8μM), MLCK (Ki=97μM) and PKC (Ki=6μM). Also inhibits myosin light chain kinase. Induces apoptotic DNA fragmentation and cell death. Inhibits telomerase activity in treated NPC-076 cells. Cell permeable.

Supplier: Enzo Life Sciences

Inhibitor of p53/MDM2 interaction

Supplier: Enzo Life Sciences

Potentiates PKC activity

Supplier: Enzo Life Sciences

Host: Rabbit

Supplier: Enzo Life Sciences

Host: Goat