- Antibody type:Primary
- Antigen name:ZAP70 Tyr493
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Western blot:Yes
- Form:Liquid
- Gene ID:7535
- Antigen synonyms:p-Zap-70Y292|ZAP-70|Tyrosine-protein kinase ZAP-70|TZK|Zap-70Tyr493|70 kDa zeta-associated protein|ZAP 70|ZAP-70=protein tyrosine kinase Syk homolog {SH2-like and C-terminal kinase domains}|zeta-associated protein 70|Syk-related tyrosine kinase. SRK|ZAP70|p-ZAP70 Y292|STD|p-Zap-70Tyr292|70 kDa zeta-chain associated protein|ZAP70_HUMAN|ZAP70 phospho Y493
- Modification:Phosphorylation (Tyr493)
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:68 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic phosphopeptide derived from human Zap-70 around the phosphorylation site of Tyr493
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterised by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Type: Primary
Antigen: ZAP70 Tyr493
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: