Anti-PI3 kinase p85 alpha + gamma Tyr467 + Tyr199 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
BOSSBS-3332R-A680
: Bioss
- Antibody type:Primary
- Antigen name:PI3 kinase p85 alpha + gamma Tyr467 + Tyr199
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rabbit,Human,Rat,Mouse
- Western blot:Yes
- Form:Liquid
- Gene ID:5295
- Antigen synonyms:Phosphatidylinositol 3-kinase regulatory subunit alpha|p85-ALPHA|p85|PI3-kinase regulatory subunit alpha|Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha|PI3K regulatory subunit alpha|GRB1|PtdIns-3-kinase regulatory subunit alpha|IMD36|PI3-kinase subunit p85-alpha|PtdIns-3-kinase regulatory subunit p85-alpha|PIK3R1|AGM7
- Modification:Phosphorylation (Tyr467 + Tyr199)
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:85/55 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic phosphopeptide derived from human PI3K around the phosphorylation site of p85 alphaTyr467
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Type: Primary
Antigen: PI3 kinase p85 alpha + gamma Tyr467 + Tyr199
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat; Rabbit