Human Recombinant FGF-7/KGF (from E. coli)

Supplier: Shenandoah Biotechnology

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Supplier: Shenandoah Biotechnology

About this item

Fibroblast growth factor 7 (FGF-7), also known as keratinocyte growth factor (KGF), is a potent mitogen that regulates epithelial cell migration and differentiation. FGF-7 is produced by mesenchymal cells and binds in high affinity to a splice variant of FGF receptor 2 (FGFR2-IIIb). The mitogenic activity of FGF-7 acts predominantly on keratinocytes, but not on fibroblast or endothelial cells. FGF-7 expression is upregulated after acute and chronic injury, suggesting that FGF-7 functions during the healing of injured epithelial cells. FGF-7 also induces the formation of the apical ectodermal ridge during limb development.

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Low endotoxin
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FGF7 expression is upregulated after acute and chronic injury, suggesting that FGF7 functions during the healing of injured epithelial cells. FGF7 also induces the formation of the apical ectoderm ridge during limb development.

Caution: This product is for research use only and is not for use in humans.

Specifications

Conjugation:
Unconjugated
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
–20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0,1
Biological activity:
Bioactivity Assay: 4MBr-5 cell proliferation, ED₅₀ ≤60 ng/ml, Bioactivity ≥1,7×10⁴ units/mg
Gene ID:
P21781
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
Y
Protein synonyms:
KGF
Protein/peptide name:
FGF-7 / KGF (AF)
Purity:
≥90%
Molecular weight:
19 kDa
Sequence:
MACNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT
Endotoxin level:
Low
Formulation:
20 mM Sodium phosphate, 0,5 M Sodium chloride, pH 7,5
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT
Tested applications:
Bioassay