Human Recombinant IL-17F (from E. coli)

Supplier: Shenandoah Biotechnology

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Supplier: Shenandoah Biotechnology

About this item

Interleukin 17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes. IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin 6 (IL-6), interleukin 8 (IL-8), and granulocyte macrophage colony-stimulating factor (GM-CSF) cytokines. IL-17F also functions to regulate matrix turnover rates, inhibit endothelial cell angiogenesis, and induce the endothelial cell expression of interleukin 2 (IL-2), monocyte chemoattractant protein-1 (MCP-1), and transforming growth factor beta 1 (TGF-b1).

High quality
Low endotoxin
Affordable

Caution: This product is for research use only and is not for use in humans.

Specifications

Conjugation:
Unconjugated
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
–20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0,1
Biological activity:
Bioactivity Assay: Production of IL-6 from mouse NIH 3T3 cells, ED₅₀ ≤100 ng/ml, Bioactivity ≥1,0×10⁴ units/mg
Gene ID:
Q96PD4
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
Y
Protein synonyms:
IL-17F|Interleukin-17F
Protein/peptide name:
IL-17F (AF)
Purity:
≥95%
Molecular weight:
15,0/30,1 kDa
Sequence:
MRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ
Endotoxin level:
Low
Formulation:
0,1% Trifluoroacetic acid (TFA)
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT
Tested applications:
Bioassay