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Human recombinant Tropomyosin alpha-3 (from E. coli)
Human recombinant Tropomyosin alpha-3 (from E. coli)
  PRSI92-078
 :  ProSci Inc.
 :  
Human recombinant Tropomyosin alpha-3 (from E. coli)
  PRSI92-078
 :  ProSci Inc.
 :  

 

  • Pk:
    50 µG
  • Protein/peptide type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Protein synonyms:
    hTM5|Tropomyosin-5|Tropomyosin-3|Tropomyosin Alpha-3 Chain|TPM3|Gamma-Tropomyosin
  • Protein/peptide name:
    Tropomyosin alpha-3
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    29 kD
  • Sequence:
    Met1-Met248
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

 

 

Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the calcium dependent regulation of vertebrate striated muscle contraction. Defects in TPM3 are the cause of thyroid papillary carcinoma. Mutations in the TPM3 gene cause autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are linked with cancer.

  • This recombinant protein can be used for biological assays. For research use only.