Human recombinant Epcr (from HEK293 cells)
Catalog # PRSI96-636
Supplier: ProSci Inc.
CAS Number:
Specifications
- Pk:100 µG
- Protein/peptide type:Recombinant
- Source:HEK293 cells
- Species:Human
- Protein synonyms:EPCR|APC receptor|CCCA|CD201|PROCR|CCD41
- Protein/peptide name:Epcr
- Purity:>95% as determined by SDS-PAGE.
- Molecular weight:48.6 kDa
- Formulation:Lyophilized, 50 mM tris, 100 mM glycine, pH7.5
- Tested applications:Western Blot
Specifications
About this item
Endothelial protein C receptor (PROCR) is also known as Activated protein C receptor (APC receptor), Endothelial cell protein C receptor, CD antigen CD201. PROCR / EPCR / CD201 is a N-glycosylated protein, with a soluble form exists. PROCR is probably released by a metalloprotease. PROCR seems to have the same activity as the membrane-bound form. PROCR / EPCR / CD201 is expressed strongly in the endothelial cells of arteries and veins in heart and lung. PROCR binds activated protein C and enhances protein C activation by the thrombin - thrombomodulin complex. PROCR plays a role in the protein C pathway controlling blood coagulation.