Separations of more than one hundred chiral compounds have been achieved using our unique DEX columns, and DEX columns continue to demonstrate stability after hundreds of temperature program cycles. By adding β or γ cyclodextrin to our bonded Rtx-1701 stationary phase, we greatly enhance overall utility and column lifetime for our chiral columns, compared to columns that have pure cyclodextrin stationary phases. 2,3-di-O-ethyl-6-O-tert-butyl dimethylsilyl beta cyclodextrin added into 14% cyanopropylphenyl/86% dimethyl polysiloxane