- Antibody type:Primary
- Antigen name:Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3G
- Antigen symbol:APOBEC3G
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Cross adsorption:No
- Form:Lyophilized
- Gene ID:60489
- Antigen synonyms:dJ494G10.1|bK150C2.7|ARP9|ARCD|A3G|CEM-15|CEM15|MDS019|ARP-9
- Storage temperature:At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
- Immunogen:E.coli-derived human APOBEC3G recombinant protein (Position: E191-N384).
- Size:100 μg
- Pk:100 µG
APOBEC3G (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G) is a human enzyme encoded by the APOBEC3G gene. This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.
1. Chelico L, Prochnow C, Erie DA, Chen XS, Goodman MF (2011)."Structural model for deoxycytidine deaminaton mechanism of the HIV-1 inactivation enzyme APOBEC3G". The Journal of Biological Chemistry 285(21): 16195–205.
2. Li X, Ma J, Zhang Q, Yin X, Zhai C, You X, Yu L, Guo F, Zhao L, Li Z, Zeng Y, Cen S (2011). "Functional analysis of the two cytidine deaminase domains in APOBEC3G". Virology 414 (2): 130–136.
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.