The DATK32 antibody is specific for a combinatorial epitope of the mouse integrin alpha 4/beta 7 (LPAM-1) heterodimer. LPAM-1 is expressed on most mature lymphocytes and sub-populations of thymocytes and bone marrow cells. It is involved in lymphocyte adhesion and migration and is a receptor for several extracellular matrix proteins including VCAM-1, fibronectin, and MAdCAM-1.
DATK32 is reported to induce LPAM-1 dependent lymphocyte aggregation and block adhesion to VCAM-1, fibronectin, and MAdCAM-1.
Type: Primary
Antigen: LPAM-1
Clonality: Monoclonal
Clone: DATK32
Conjugation: Biotin
Epitope:
Host: Rat
Isotype: IgG2a
Reactivity: Mouse
- Catalog No:
- 30-5887-U025
- 30-5887-U100
- Antigen symbol:
- LPAM-1
- LPAM-1
- Antigen synonyms:
- CD49d/beta7|alpha4beta7 Integrin|LPAM-1
- CD49d/beta7|alpha4beta7 Integrin|LPAM-1
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- Biotin
- Biotin
- Clone:
- DATK32
- DATK32
- Reactivity:
- Mouse
- Mouse
- Host:
- Rat
- Rat
- Isotype:
- IgG2a
- IgG2a
- Flow cytometry:
- Yes
- Yes
- Neutralisation:
- Yes
- Yes
- Cross adsorption:
- none
- none
- Storage temperature:
- Store undiluted at 2...8 °C, protect from light, do not freeze
- Store undiluted at 2...8 °C, protect from light, do not freeze
- Shipping temperature:
- Ice
- Ice
- Tested applications:
- Flow Cytometry
- Flow Cytometry
: KIMBERLY CLARK
: VWR Collection
: VWR Chemicals
: VWR Collection
: VWR Collection
: VWR Chemicals
: VWR Collection
: VWR Collection