Anti-CDC123 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog # BOSSBS-7781R-FITC

Supplier: Bioss

Catalog # BOSSBS-7781R-FITC

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
Cell Division Cycle 123
Antigen symbol:
CDC123
Clonality:
Polyclonal
Conjugation:
FITC (Fluorescein Isothiocyanate)
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Cross adsorption:
No
Form:
liquid
Gene ID:
8872
Antigen synonyms:
C10orf7|D123
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature:
Store at –20 °C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

Required for S phase entry of the cell cycle.The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin dependent kinases (Cdks) and cell division control (Cdc) proteins. Cdc123 (Cell division cycle protein 123), also known as D123, is a 336 amino acid cytoplasmic protein that is involved in cell cycle control. Widely expressed with high expression in thymus, spleen, ovary, testis, small intestine and leukocytes, Cdc123 functions to destabilize Chfr (checkpoint with forkhead and ring finger domain) proteins which, when accumulated, block the G to S phase transition. Cdc123 prevents the Chfr proteins from collecting in the cell, thereby allowing the cell to enter the S phase. Due to its role in cell cycle control, Cdc123 is thought to be a basal marker for luminal breast cancers.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CDC123
Clonality: Polyclonal
Clone: 0
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: