"Stemcell Technologies"

Supplier: Stemcell Technologies

Rat monoclonal IgG2a antibody against mouse CD62L (L-selectin), PE-conjugated.

Supplier: Stemcell Technologies

Semi-solid methylcellulose-based medium for hybridoma selection and cloning, with HAT (serum-containing).

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD138 (syndecan-1), PE-conjugated.

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched human B cells

Supplier: Stemcell Technologies

Granulocyte colony-stimulating factor (G-CSF) is a member of the CSF family of glycoproteins that regulate hematopoietic cell proliferation, differentiation, and function. It is a key cytokine involved in the production of neutrophils and the stimulation of granulocyte colony formation from hematopoietic progenitor cells (Metcalf and Nicola). G-CSF causes a range of effects including a transient reduction of SDF-1 expression (Petit et al.), the activation of metalloproteases that cleave VCAM-1 (Levesque et al.), and the release of norepinephrine from the sympathetic nervous system (Katayama et al.), leading to the release or mobilization of hematopoietic stem cells from the bone marrow into the periphery. The G-CSF receptor is expressed on a variety of hematopoietic cells, including myeloid-committed progenitor cells, neutrophils, granulocytes, and monocytes. In addition to hematopoietic cells, G-CSF is also expressed in cardiomyocytes, neuronal cells, mesothelial cells, and endothelial cells. Mouse G-CSF was first purified from cultures of the WEHI-3B myelomonocytic leukemia cell line as the inducer of the terminal differentiation of WEHI-3B and other myeloid leukemia cell lines (Nicola et al.). It was later cloned in monkey COS cells from a cDNA library prepared with mRNA derived from mouse fibrosarcoma NFSA cells that produce G-CSF constitutively (Tsuchiya et al.). Binding of G-CSF to its receptor leads to activation of the JAK/STAT, MAPK, PI3K, and AKT signal transduction pathways.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, cynomolgus, cow CD117 (c-Kit), APC-conjugated.

Supplier: Stemcell Technologies

Methylcellulose-based medium with recombinant cytokines for human cells. 1×100 ml bottle.

Supplier: Stemcell Technologies

Integrated workflow containing tools to isolate and expand CD34+ progenitor cells from peripheral blood and their subsequent reprogramming to iPS cells.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2a antibody against mouse CD45.1, biotin-conjugated.

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched human B cells.

Supplier: Stemcell Technologies

cGMP, human T cell activation and expansion reagent.

Supplier: Stemcell Technologies

The EasySep™ 'The Big Easy' magnet is designed for cell separation procedures using EasySep™ reagents when processing a large number of cells, or when using RoboSep™.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, chimpanzee CD3, PerCP-Cy5.5-conjugated

Supplier: Stemcell Technologies

Supplement for expansion of mouse and rat neural stem and progenitor cells.

Supplier: Stemcell Technologies

Rat monoclonal antibody against mouse, hamster CD4, PE-conjugated.

Supplier: Stemcell Technologies

Rat monoclonal antibody against mouse, hamster CD4, PerCP-Cy5.5-conjugated.