"Stemcell Technologies"

Supplier: Stemcell Technologies

Rat monoclonal IgG2a antibody against mouse, toad CD8a, FITC-conjugated.

Supplier: Stemcell Technologies

Cell culture medium for establishment and maintenance of mouse pancreatic exocrine organoids.

Supplier: Stemcell Technologies

Rat monoclonal IgG2a antibody against mouse CD138 (syndecan-1), biotin-conjugated.

Supplier: Stemcell Technologies

For detection and measurement of human immunoglobulin E.

Supplier: Stemcell Technologies

Immunodensity depletion of CD8+ T cells.

Supplier: Stemcell Technologies

Serum-free and conditioned medium-free cell culture medium for establishment and maintenance of human intestinal organoids.

Supplier: Stemcell Technologies

Culture medium kit for establishment and maturation of human cerebral organoids.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2a antibody against human, rhesus, cynomolgus CD184 (CXCR4), PE-conjugated.

Supplier: Stemcell Technologies

Interleukin 13 (IL-13) is a cytokine important in type 2 immune responses and is expressed by T helper type 2 (Th2) cells and group 2 innate lymphoid cells (ILC2s) (Pulendran and Artis). IL-13 binds a receptor composed of IL-4Ra and IL-13Ra1 or IL-13Ra2 (Wynn 2003). IL-13 receptor is expressed on B cells and promotes B cell proliferation, induces class switching to IgG4 and IgE, and functions in the recruitment and activation of IgE-producing B cells (Hershey). The receptor is also expressed on basophils, eosinophils, mast cells, endothelial cells, fibroblasts, monocytes, macrophages, respiratory epithelial cells, and smooth muscle cells (Hershey). Signaling through the IL-13 receptor activates the JAK/STAT and IRS-1/IRS-2 pathways. in vivo, IL-13 has a role in resistance to extracellular helminth parasites by regulating gastrointestinal parasite expulsion, as well as in airway hyperresponsiveness, allergic inflammation, tissue remodeling, tumor cell growth, and fibrosis (Wynn 2015). Secreted IL-13 is a protein consisting of 112 amino acids with a molecular mass of 10 kDa (Hershey). Human IL-13 is not species-specific but has greater activity on human cells compared to mouse cells (Hershey).

Supplier: Stemcell Technologies

Mouse monoclonal IgM antibody against human, mouse, rat oligodendrocyte marker O4, unconjugated.

Supplier: Stemcell Technologies

Rat monoclonal IgG2b antibody against mouse CD4, PE-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2a antibody against human, chimpanzee, common marmoset CD45RO, PE-conjugated.

Supplier: Stemcell Technologies

Immunomagnetic positive selection of CD11b+ cells from human peripheral blood mononuclear cells (PBMCs) or leukapheresis samples.

Supplier: Stemcell Technologies

Dulbecco's Modified Eagle's Medium (DMEM) with 1000 mg/L D-glucose.

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched mouse pan-naïve T cells

Supplier: Stemcell Technologies

Stimulating T cells with JCV (LT) Peptide Pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. This peptide pool is a lyophilised mixture of 170 peptides from large T antigen (LT) of JC polyomavirus (JCV), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 688 on LT. LT is detectable during JCV latency (Rossi et al.), and in immunocompromised patients with JVC-associated pathologies such as progressive multifocal leukoencephalopathy (PML) (Delbue et al.). In PML, LT has been associated with activating the promoter of survivin, an anti-apoptotic protein (Del Valle et al.). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.