"Stemcell Technologies"

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD83, APC-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgM antibody against human, rhesus, rabbit TRA­1­60 (podocalyxin), Alexa Fluor® 488-conjugated.

Supplier: Stemcell Technologies

Propidium Iodide (PI) is a red-fluorescent cell viability dye which is excluded from live cells with intact membranes, but penetrates dead or damaged cells and binds to DNA and RNA by intercalating between the bases.

Supplier: Stemcell Technologies

Rat monoclonal IgG2a antibody against mouse Sca1 (Ly-6A/E), biotin-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against mouse, rat, guinea pig CD90/CD90.1, FITC-conjugated.

Supplier: Stemcell Technologies

Hamster (Armenian) monoclonal IgG1 antibody against mouse CD3e, FITC-conjugated.

Supplier: Stemcell Technologies

Tumor necrosis factor-α (TNF-α) is a pro-inflammatory cytokine that activates NF-κB, MAPK, and PI3K/AKT pathways. Activated T cells and macrophages are the primary producers of TNF-α in response to inflammation and infectious conditions. Many other cell types have been shown to produce TNF-α, among them B cells, NK cells, mast cells, neutrophils, dendritic cells, microglia, endothelial cells, smooth muscle cells, cardiomyocytes, and fibroblasts. TNF-α has cytotoxic effects on cancer cells in vitro by stimulating anti-tumor immunosuppressive responses. TNF-α stimulates expression of E- and P-selectins, thus facilitating adhesion of neutrophils, monocytes, and memory T cells to activated platelets and endothelial cells (Zelová andamp; Hosek). Other effects of TNF-α include vasodilatation and edema formation.

Supplier: Stemcell Technologies

Complete medium for differentiating mouse mesenchymal stem cells and embryonic fibroblasts into osteoblasts.

Supplier: Stemcell Technologies

Fibroblast growth factor 18 (FGF-18) is a growth factor and member of the FGF subfamily. FGF-18 is most similar to FGF-8 and FGF-17, and is secreted in adult lung and developing tissues (Ohbayashi et al.). FGF-18 signals through FGF receptor 3 (FGFR3) to regulate proliferation, differentiation, and matrix production of articular and growth plate chondrocytes in vivo and in vitro (Davidson et al.). FGF-18 has skeletal functions and protects articular cartilage by gene expression profiling and regulates proliferation and differentiation of midline cerebellar structures (Mori et al.). Also, recombinant human FGF-18 has been shown to effectively regulate hair growth (Song et al.).

Supplier: Stemcell Technologies

Serum- and xeno-free medium and attachment substrate for expansion of human pluripotent stem cell-derived endothelial cells.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human CD56 (NCAM), unconjugated.

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched mouse pan-naïve T cells

Supplier: Stemcell Technologies

Bone morphogenetic protein 4 (BMP-4) is a member of the highly conserved transforming growth factor β (TGF-β) superfamily. Mature BMP-4 is a disulfide-linked homodimeric protein consisting of two 116-amino-acid residue subunits, and is generated by the proteolytic removal of the signal peptide and propeptides (Xiao et al.). BMP-4 binds to type I and type II receptors on cells. This binding results in the phosphorylation of receptor 1, which in turn results in the phosphorylation of Smad proteins, which then go on to act as transcription factors (Zhang et al.). BMPs have been shown to be key regulators of embryogenesis and are known to play a role in the growth and differentiation of various cell types, including embryonic stem (ES) cells, induced pluripotent stem (iPS) cells, mesenchymal cells, epithelial cells, hematopoietic cells, and neuronal cells (Chadwick et al.; Graham et al.; Jones et al.; Lengerke et al.; Zhang et al.).

Supplier: Stemcell Technologies

Mouse monoclonal IgG2a antibody against human, chimpanzee, common marmoset CD45RO, unconjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2b antibody against human, rhesus, cynomolgus CD4, PE-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, rat CD36, unconjugated.