652 Results for: "Shenandoah Biotechnology"

Supplier: Shenandoah Biotechnology

Macrophage inflammatory protein-1 alpha (MIP-1-alpha), also known as CCL3, is a cytokine produced by macrophages. The MIP-1-alpha an d MIP-1-beta heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1). 1 * 2 µG

Supplier: Shenandoah Biotechnology

Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to acti vate receptor tyrosine kinase RET signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to acti vate receptor tyrosine kinase RET signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a c ritical role in the maintenance, survival, and differentiation of hematopoietic stem cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Macrophage inflammatory protein-4 (MIP-4), also called CCL18, is a chemokine expressed in the lymph nodes, lungs, placenta, and bone marrow. acute lymphocytic leukemia B cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Growth hormone (GH) is an important mitogenic growth factor that is synthesized, stored, and secreted by somatotropic cells of the a nterior pituitary gland. GH stimulates growth, cell reproduction, and cell regeneration. 1 * 5 mg

Supplier: Shenandoah Biotechnology

Interleukin 3 is a cytokine that is produced by activated T cells and mast cells. IL-3 induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cell 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 32 alpha (IL-32a) is one of six known splice variants of the IL-32 gene.  IL-32a induces the macrophage production of in flammatory cytokines, such as interleukin 8, tumor necrosis factor-alpha (TNF-a), and macrophage inflammatory protein 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin 2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 9 (IL-9) is a cytokine produced by type 2 T helper (Th2) cells and regulates hematopoietic cells. IL-9 signals through the interleukin 9 receptor (IL9R) to activate STAT signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Monocyte chemotactic protein 3 (MCP-3), also called CCL7, is produced by macrophages and tumor cell lines. MCP-3 signals through th e G protein-coupled receptors CCR1, CCR2, and CCR3. 1 * 2 µG

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Interleukin 21 (IL-21) is a member of the common-gamma chain family of cytokines that are involved in immunoregulation. IL-21 is no rmally expressed by activated CD4+ T cells. 1 * 2 µG

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Interleukin-19 (IL-19) is a member of the interleukin 10 (IL-10) cytokine family and is produced by B cells and monocytes. IL-19 bi nds the interleukin 20 receptor complex (IL-20R) to activate STAT3 signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 21 (IL-21) is a member of the common-gamma chain family of cytokines that are involved in immunoregulation. IL-21 is no rmally expressed by activated CD4+ T cells and is aberrantly expressed in Hodgkin lymphoma cells. classes in B cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 21 (IL-21) is a member of the common-gamma chain family of cytokines that are involved in immunoregulation. IL-21 is no rmally expressed by activated CD4+ T cells and is aberrantly expressed in Hodgkin lymphoma cells. classes in B cells. 1 * 100 µG

Supplier: Shenandoah Biotechnology

Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Lepti n acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. 1 * 5 µG

Supplier: Shenandoah Biotechnology

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-a, TGF-b and EGF signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-a, TGF-b and EGF signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine that is produced by monocytes, macrophages, and dendritic cells (DCs). IL -1β signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MY 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferati on and megakaryocyte differentiation. IL-11 binds the IL-11Ralpha (IL-11Rα) receptor to activate JAK downstream signal 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 13 (IL-13) is a cytokine secreted from type 2 T helper (Th2) cells. IL-13 also regulates immune cell inflammation in re sponse to the pathophysiological changes of surrounding non-immune cells. 1 * 2 µG

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Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelia l cells. 1 * 2 µG

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Bone morphogenic protein 2 (BMP2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bo ne and cartilage development. 1 * 2 µG

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Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelia l cells. IL-33 functions to induce type 2 cytokine production in polarized Type 2 T helper (Th2) cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Oncostatin M (OSM) is a cytokine that is produced by macrophages, dendritic cells, and T lymphocytes during inflammatory events. Th e Type-I and Type-II OSM receptors are located on the cell surface of endothelial and tumor cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF -A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Epstein-Barr virus induced gene 3 (EBI3), is a secreted glycoprotein belonging to the hematopoietin receptor family related to the p 40 subunit of interleukin 12. EBI3 expression is induced in B-lymphocytes in response to Epstein-Barr virus infectio 1 * 2 µG

Supplier: Shenandoah Biotechnology

Epidermal growth factor (EGF) is a growth factor that stimulates the proliferation, differentiation, and survival of epithelial and epidermal cells. 1 * 1 mg

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Epidermal growth factor (EGF) is a growth factor that stimulates the proliferation, differentiation, and survival of epithelial and epidermal cells. 1 * 500 µG

Supplier: Shenandoah Biotechnology

Fibroblast growth factor 9 (FGF9) is a mitogen and survival factor for nerve and mesenchymal cells. FGF9 functions as an autocrine and paracrine factor to support the growth and survival of motor neurons and prostate tissue. 1 * 2 µG