"Other Essentials"

Supplier: AAT Bioquest

DiI, DiO, DiD and DiR dyes are a family of lipophilic fluorescent stains for labeling membranes and other hydrophobic structures.

Supplier: AAT Bioquest

Compared to other commercial hydrogen peroxide solutions, our formulated hydrogen peroxide solution is much more stable.

Supplier: MERCK PRODUCTION CHEMICALS

Bole white (kaolin), powder, EMPROVE® EXPERT BP, Ph. Eur., extra pure suitable for use as excipient, for internal use low bacterial content, SAFC®

Supplier: ProSci Inc.

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex.DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Supplier: Avantor Fluid Handling

Provides longer life than other platinum and peroxide silicone tubing formulations.

Supplier: VELP SCIENTIFIC

The FP4, FC S, and JLT Series assist laboratory technicians in the environmental sector by providing tools for conducting the jar test and leaching test, which are essential for water treatment and environmental protection. These tests help determine the most effective methods for improving water quality and assessing the potential environmental risks posed by pollutants.

Supplier: Bioss

Essential for mesoderm formation and axial patterning during embryonic development.

Supplier: Bioss

Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.

Supplier: ProSci Inc.

Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. This protein is normally expressed in the dendritic cells, macrophages, microglia, eosinophils, fibroblasts, endothelial cells, and most tumour cells. IDO activity is associated with immunosuppression and immune attenuation. Several studies showed that IDO can contribute to immune escape when expressed directly in tumour cells or when expressed in immunosuppressive antigen presenting cells such as tolerogenic dendritic cells or tumour associated macrophages. IDO also is a promising therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterised by pathological immune suppression.

Supplier: MP Biomedicals

Chromogenic substrate for trypsin and other proteolytic enzymes.

Supplier: Sartorius

Agar media in bottles are the time and cost-effective alternative for casting plates.

Supplier: ProSci Inc.

MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.

Supplier: ProSci Inc.

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.

Supplier: Avantor Fluid Handling

Provides longer life than other platinum and peroxide silicone tubing formulations.

Supplier: Avantor Fluid Handling

Provides longer life than other platinum and peroxide silicone tubing formulations.

Supplier: IKA

The compact immersion circulators of the lite series are powerful and of high quality, with a focus on essential basic functions, excellent performance and efficient operation. ICC 100 lite is suitable for tempering liquids up to 100 °C and internal circulation.