"Other Essentials"

Supplier: ProSci Inc.

IKK alpha Antibody: Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNF alpha and bacteria product LPS. NF-kappa B is associated with I kappa B proteins in the cell cytoplasm, which inhibit NF-kappa B activity. The long-sought I kappa B kinase (IKK), which phosphorylates I kappa B, and mediates I kappa B degradation and NF-kappa B activation, was recently identified by several laboratories. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta ). IKK alpha and IKK beta interact with each other and both are essential for the NF-kappa B activation. IKK alpha specifically phosphorylates I kappa B-alpha. IKK alpha is expressed in a variety of human tissues.

Supplier: ProSci Inc.

IKK beta Antibody: Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNF alpha , and bacteria product LPS. NF-kappa B is associated with I kappa B proteins in the cell cytoplasm, which inhibit NF-kappa B activity. The long-sought I kappa B kinase (IKK), which phosphorylates I kappa B, and mediates I kappa B degradation and NF-kappa B activation, was recently identified by several laboratories. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta ). IKK alpha and IKK beta interact with each other and both are essential for NF-kappa B activation. IKK beta phosphorylates both I kappa B-alpha and I kappa B-beta. IKK beta is expressed in variety of human tissues.

Supplier: ProSci Inc.

SESTD1 Antibody: SESTD1 was initially identified in mutant zebrafish with defects in the spontaneous contraction and touch response as a novel gene, solo, encoding a protein containing SEC14 and spectrin repeat domains. Other experiments indicated that SESTD1 interacts with the TRPC4 and TRPC5, members of the transient receptor potential channel family, via the TRPC calmodulin- and inositol 1, 4, 5-triphosphate receptor-binding domain and is essential for efficient receptor-mediated activation of TRPC5, suggesting that SESTD1 is a novel regulator of these TRPC proteins.

Supplier: ProSci Inc.

CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Supplier: Merck

The certified reference material (CRM) is intended to be used as a calibrant for chromatography and other analytical techniques. The CRM may also find the following uses:

Supplier: LEICA MICROSYSTEMS

Leica DM750 microscopes have been specifically developed to facilitate science teaching. DM750 is designed essentially for the versatile needs of advanced life science courses and for professional training, such as in medical, veterinary and dental schools.

Supplier: Sartorius Balances

Cubis® II MCE high-capacity toploading balances with essential user interface offer a maximum load between 11,2 and 70,2 kg and readability between 0,1 and 1 g provide the ideal model for every application.

Supplier: Bioss

Essential for the control of the cell cycle at the G2/M (mitosis) transition.

Supplier: Bioss

Essential for the control of the cell cycle at the G2/M (mitosis) transition.

Supplier: Avantor

The quality of many BAKER ANALYZED™ Reagents meets or exceeds the requirements set forth by the American Chemical Society (ACS). These solvents are essential for any chemical stockroom.

Supplier: MP Biomedicals

DL-Threonine is an essential α - amino acid classified as polar which has two chiral centers. In plants and micro-organisms, threonine is synthesized from aspartic acid via aspartyl - semialdehyde and homoserine.

Supplier: AAT Bioquest

Cy3® dye is one of the most common cyanine dyes used for labeling proteins, nucleic acids and other biological molecules.

Supplier: VWR Collection

The ideal rest for round bottom flasks and other round bottom glass vessels. Compressed cork, natural.

Supplier: MERCK PRODUCTION CHEMICALS

Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000 are not likely to be present.
Corresponds to Ph. Eur., BP, USP, FCC

Supplier: Avantor Fluid Handling

Outlast and outperform other tubing with 10000 hours of tubing life.

Supplier: Avantor Fluid Handling

Outlast and outperform other tubing with 10,000 hours of tubing life.