5268 Results for: "ENZO LIFE SCIENCES"
N-Oleoyldopamine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Endogenous TRPV1 agonist (Ki=36nM, EC50=36nM) with weak affinity for rat CB1 receptor (Ki=1.6µM). Potent inhibitor of 5-lipoxygenase (IC50=7.5nM) and of early and late events in TCR mediated T cell activation. Inhibits NF-κB dependent transcriptional activity without affecting either degradation of the cytoplasmic NF-κB inhibitory protein, IκBα, or DNA binding activity.
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Dihydroceramide C8 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Negative control for C8 ceramide.
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Why Choose Corning Fetal Bovine Serum?
Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.
Nomilin ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Carciogenesis inhibitor
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Dasatinib ≥99% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Potent tyrosine kinase inhibitor
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Ruthenium(III) chloride oxide ≥90% (metals basis)
Supplier: ENZO LIFE SCIENCES
Blocks TRPV1. Capsaicin and calcium antagonist. Inhibitor of Ca²⁺/Mg2⁺-ATPase.
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Lucigenin ≥98% (by HPLC), Ultrapure
Supplier: ENZO LIFE SCIENCES
Chloride dye
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Wash buffer, 3 packs of salts, SignaSure®
Supplier: ENZO LIFE SCIENCES
SignaSure® Wash Buffer is formulated for use with alkaline phosphatase-linked detection reagent assay systems.
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Momelotinib ≥97% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Selective inhibitor of JAK1 and JAK2 kinases including the JAK2 V617F mutant
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EQ2 NHS ester amine-reactive quencher dye
Supplier: ENZO LIFE SCIENCES
Amine-reactive quencher dye has a broad visible absorption but no detectable fluorescence emission in fluorescence resonance energy transfer (FRET) applications.
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Anti-DR6 Rat Monoclonal Antibody
Supplier: ENZO LIFE SCIENCES
Apoptosis is induced by certain cytokines including TNF and Fas ligand (CD95L) of the TNF family through their death domain containing receptors, TNF-R1 and Fas (CD95). Several death receptors including DR3, TRAIL-R1, and TRAIL-R2 were identified. A death domain containing receptor in the TNF-R family was cloned and termed DR6 for death receptor-6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-κB and JNK. DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified yet. T cells from DR6-deficient mice showed preference toward Th2 differentiation in vitro, suggesting that DR6, working through JNK functions to attenuate the Th2 response. Other studies of DR6-targeted mutant mice demonstrated that DR6 functions as a regulatory receptor for mediating CD4(+) T cell activation and maintaining proper immune responses.
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Coumermycin A1 ≥97% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits supercoiling activity of gyrase by binding to the gyrase B domain – but more importantly is a novel cell permeable dimerizing ligand for gyrase B fusion proteins. Has been used to dimerize a variety of signaling proteins such as Raf1, JAK2, Tyk and L-selectin.
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4-α-Phorbol-12-myristate-13-acetate ≥99% (by HPLC, TLC), film
Supplier: ENZO LIFE SCIENCES
PKC activator
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Wash buffer concentrate
Supplier: ENZO LIFE SCIENCES
Liquid. TRIS buffered saline containing detergents.
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Streptomycin sulphate (from Streptomyces species)
Supplier: ENZO LIFE SCIENCES
Antibiotic. Inhibits prokaryote protein synthesis. Binds to the S12 protein of the 30S ribosomal subunit. Effective against Gram-negative and Gram-positive bacteria. Mutation in rpsL (the gene for S12 ribosomal protein) prevents binding of streptomycin to ribosome. Inactivated by aminoglycoside phosphotransferase.
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Nadifloxacin ≥98%
Supplier: ENZO LIFE SCIENCES
Fluoroquinolone with broad spectrum activity against Gram-negative and Gram-positive bacteria. Inhibits the generation of O2- and OH radicals by neutrophils. Inhibits the production of inflammatory cytokines.
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FGIN-1-27 ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Benzodiazepine receptor ligand.
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Catalase fluorometric detection kit
Supplier: ENZO LIFE SCIENCES
The Catalase fluorometric detection kit provides a higher throughput sensitive method for measuring catalase activity in just one hour. This is a homogeneous mix-and-read assay that enables you to monitor multiple time points for a kinetic read. Positive control is provided.
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Human Recombinant EGF (from E. coli)
Supplier: ENZO LIFE SCIENCES
Produced in E.coli.
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Anti-c-FLIP Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
cFLIP, is a cellular homologue of the viral protein, vFLIP. cFLIP contains two death effector domains (DEDs) and is expressed as either a short or long splice variant called cFLIPs and cFLIPL, respectively.
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Anti-TLR9 Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
The TLRs (Toll-like receptors) are a group of evolutionarily conserved pattern recognition molecules that play a key role in host defense during microbial infection by regulating both innate and adaptive immune responses. TLRs are type I transmembrane proteins with ectodomains containing interspersed leucine-rich repeat (LRR) motifs that are involved in the recognition of various microbial ligands.
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Anti-CNR2 Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
The cannabinoid receptors CB1 and CB2 are GPCRs named for their signaling function in response to cannabinoid drugs such as Delta9-tetrahydrocannabinol (Delta9-THC). In addition to Delta9-THC and its synthetic analogs, CB1 and CB2 receptors are bound by endogenous eicosanoid ligands (e.g. anandamide), and signal via Gi/o alpha subunits to regulate adenylyl cyclase activity (generally inhibitory), ion channel activation, intracellular Ca2+ levels, nitric oxide synthase activation, and immediate early gene expression. CB1 and CB2 signals in turn regulate neurological and immunological functions such as inhibition of neurotransmitter release and immune cell migration, antigen processing, and cytokine production.
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Anti-ACTB Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
Actin is one of the major proteins of the cytoskeleton. It regulates contractile potential in muscle tissues and helps to control the shape as well as the motility of non-muscle cells. Actin is expressed in all eukaryotic cells. In higher eukaryotes, there are six isoforms of actin.
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Anti-JNK2 Mouse Monoclonal Antibody [clone: 12C5]
Supplier: ENZO LIFE SCIENCES
The Stress-activated protein kinases alpha and gamma (SAPKalpha and gamma), also know as c-Jun NH2-terminal kinases 1 and 2 (Jnk1/2) are serine/ threonine protein kinases belonging to the MAP kinase family. The extracellular stimuli leading to cell stress include inflammatory cytokines (via Rho and Rac), growth factors, protein synthesis inhibitors and osmotic stress amongst others. Both Jnk1 and Jnk2 must be dually phosphorylated in the activation loop, at threonine 183 and tyrosine 185, to achieve full enzymatic activity.
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Anti-CNR1 Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
The cannabinoid receptors CB1 and CB2 are GPCRs named for their signaling function in response to cannabinoid drugs such as Delta9-tetrahydrocannabinol (Delta9-THC). In addition to Delta9-THC and its synthetic analogs, CB1 and CB2 receptors are bound by endogenous eicosanoid ligands (e.g. anandamide), and signal via Gi/o alpha subunits to regulate adenylyl cyclase activity (generally inhibitory), ion channel activation, intracellular Ca2+ levels, nitric oxide synthase activation, and immediate early gene expression. CB1 and CB2 signals in turn regulate neurological and immunological functions such as inhibition of neurotransmitter release and immune cell migration, antigen processing, and cytokine production.
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Anti-SMAC/DIABLO Mouse Monoclonal Antibody
Supplier: ENZO LIFE SCIENCES
Smac/DIABLO is one of the pro-apoptotic proteins normally found in the intermembrane space of the mitochondria. In response to apoptotic stimuli, Smac/DIABLO is released into the cytosol resulting in permeabilization of the mitochondrial membrane. Cytosolic Smac/DIABLO activates caspase-9 by binding IAP proteins. Changes in the expression level of Smac/DIABLO have been demonstrated in a number of human cancers including melanoma, ovary, and prostate.
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Anti-VEGF Mouse Monoclonal Antibody [clone: 6B7]
Supplier: ENZO LIFE SCIENCES
VEGF (Vascular endothelial growth factor) is a potent polypeptide regulator of blood vessel function. VEGF promotes an array of responses in the endothelium, including hyperpermeability, endothelial cell growth, angiogenesis, and enhanced glucose transport. Several alternate splice isoforms of VEGF are known. Two high-affinity receptors for VEGF, VEGFR1 and VEGFR2, have been identified and characterized.
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Anti-JNK3 Mouse Monoclonal Antibody [clone: 4G6]
Supplier: ENZO LIFE SCIENCES
The Stress-activated protein kinases alpha and gamma (SAPKalpha and gamma), also known as c-Jun NH2-terminal kinases 1 and 2 (Jnk1/2) are serine/ threonine protein kinases belonging to the MAP kinase family. The extracellular stimuli leading to cell stress include inflammatory cytokines (via Rho and Rac), growth factors, protein synthesis inhibitors and osmotic stress amongst others. Both Jnk1 and Jnk2 must be dually phosphorylated in the activation loop, at threonine 183 and tyrosine 185, to achieve full enzymatic activity.
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Anti-IGF1R Mouse Monoclonal Antibody [clone: 2B9]
Supplier: ENZO LIFE SCIENCES
Insulin-like growth factor-I (IGF-I) is a polypeptide hormone similar in structure to insulin. It is involved in regulation of neuronal growth and development in the central and peripheral nervous system. IGF-1 is a potent inhibitor of apoptosis in neurons, and activates the Akt signaling pathway via the IGF-1R and Insulin receptors. The IGF-1R acts as a receptor for IGF-1 and the related IGF-2, and is subject to autophosphorylation on multiple tyrosine residues that regulate receptor activation and assembly of signal transduction complexes.