The water-wettable, hydroxylated exterior allows excellent flow, even with biological fluids. A gradient of polarity on the polymer surface shunts small analytes to the more hydrophobic centre of the polymer bead, where they are retained prior to the washing and elution steps. Plexa provides these performance enhancements due to a unique polymeric architecture with a non-retentive, hydroxylated, amide-free surface and a non-polar PS/DVB core for retaining small molecules.

• Fast flow, reproducible performance
• Improved extract cleanliness minimises sample matrix interferences
• Non-polar retention mechanism

Binding of proteins and lipids on the polymer surface is minimised, resulting in cleaner samples and reduced matrix interference. Plexa is ideal for high-throughput tests requiring validated performance with minimal method development. The standard non-polar retention mechanism is applicable to almost any analyte type. The performance features operate at the sample loading step, making them largely method independent.