About this item
SCF is a multipotent factor which affects cells of the myeloid, erythroid, mast, and lymphoid lineages.
- High quality
- Low endotoxin
- Lot-to-lot consistency
- Animal free
- Manufactured following GMP guidelines
Exists both as a membrane-bound and soluble form
Expressed by fibroblasts and endothelial cells promoting proliferation, migration, survival, and differentiation in hematopoietic progenitors, melanocytes, and germ cells
Promotes mast cell secretory function, chemotaxis, and adhesion
Enhances secretion of mediators in response to IgE-dependent activation
The biological activity of CTGrade GMP interleukins and growth factors is standardised, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance
Host Cell Protein: ≤30 ng/ml
Host Cell DNA: ≤0,01 ng/ml
Sterility testing: No Growth
Mycoplasma: Negative
Specifications
- Conjugation:Unconjugated
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Storage conditions:At or below –20 °C
- Endotoxin content:Endotoxin LAL (EU/µg) ≤0,05
- Biological activity:Bioactivity Assay: Proliferation of TF-1, ED₅₀ ≤15 ng/ml, Bioactivity ≥1,0x10³ IU/µg
- Gene ID:P21583
- Reconstitution instructions:Sterile water at 0,1 - 0,5 mg/ml
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:Y
- Protein synonyms:c-Kit Ligand|KL|mgF|Steel Factor
- Protein/peptide name:CTGrade GMP SCF
- Purity:≥97%
- Molecular weight:18,6 kDa
- Sequence:MEGICRNRVT NNVKDVTKLV ANLPKDYMIT LKYVPGMDVL PSHCWISEMV VQLSDSLTDL LDKFSNISEG LSNYSIIDKL VNIVDDLVEC VKENSSKDLK KSFKSPEPRL FTPEEFFRIF NRSIDAFKDF VVASETSDCV VSSTLSPEKD SRVSVTKPFM LPPVA
- Endotoxin level:Low
- Formulation:10 mM Sodium phosphate, 50 mM Sodium chloride, pH 7,5
- Nuclease-free:N
- Grade:GMP
- Shipping temperature:Ambient
- Tested applications:Bioassay